Coriell Institute for Medical Research
Colombian in Medellín, Colombia [CLM]

The biomaterials currently available for this population are shown in the table below:

Population Colombian in Medellín, Colombia [CLM]
DNA Sample Panel MGP00005
Individual DNA Samples 136
Individual Cell Cultures 136

Principal Investigator:
Gabriel Bedoya, Maria V. Parra, Universidad de Antioquia, Colombia
Andrés Ruiz-Linares, University College London

Population Description

These cell lines and DNA samples were prepared from blood samples collected in the Medellín, Colombia, metropolitan area. All of the samples are from mother-father-adult child trios. All parents in the trios identified themselves as having all four grandparents born in Colombia. Although individuals from the Medellín metropolitan area can originate in different parts of Colombia, this set of samples should not be seen as representative of the entire population of Colombia, which is regionally highly diverse. Note that the correct spelling is: Colombian and not Columbian, and also that Medellín has an accent on the (i).

These samples should not be referred to as "Hispanic" or "Latino" since these are cultural designators, encompassing populations with very diverse ancestries.

After the complete descriptor "Colombian in Medellín, Colombia" has been provided, it is acceptable to use the shorthand label "Colombian" or the abbreviation "CLM" in the remainder of the article or presentation. However, the full descriptor for the population should be provided before the shorthand labels are used; this will help to avoid the risks associated with over-generalization of findings.

It may be scientifically appropriate to pool data from these samples with data from other ancestrally related groups, when the data show that the groups have similar allele frequencies. If the groups are all from the Americas, the designation "Americas" (AMR) to describe the combined analysis panel is recommended. If only groups very closely related to the Colombians have similar allele frequencies, then another abbreviation may be used.

Additional guidance about how to refer to the populations can be found at Guidelines for Referring to the Populations in Publications and Presentations.

Policies and Guidelines


1. Wang S, Ray N, Rojas W, Parra MV, Bedoya G, Gallo C, Poletti G, Mazzotti G, Hill K, Hurtado AM, Camrena B, Nicolini H, Klitz W, Barrantes R, Molina JA, Freimer N, Bortolini MC, Salzano FM, Petzl-Erler ML, Tsuneto LT, Dipierri JE, Alfaro EL, Bailliet G, Bianchi NO, Llop E, Rothhammer F, Excoffier L, Ruiz-Linares A. (2008) Geographic patterns of genome admixture in Latin American Mestizos. PLoS Genet 4(3): e1000037.

2. Bedoya G, Montoya P, Garcia J, Soto I, Bourgeois S, Carvajal L, Labuda D, Alvarez V, Ospina J, Hedrick PW, Ruiz-Linares A. (2006) Admixture dynamics in Hispanics: a shift in the nuclear genetic ancestry of a South American population isolate. Proc Nal. Acad Sci 103(19): 7234-7239.

3. Safford F, Palacios M. (2001) Colombia: Fragmented Land, Divided Society (Latin American Histories). Oxford Univ. Press, Oxford.

4. Carvajal-Carmona LG, Soto ID, Pineda N, Ortiz-Barrientos D, Duque C, Ospina-Duque J, McCarthy M, Montoya P, Alvarez VM, Bedoya G, Ruiz-Linares A. (2000) Strong Amerind/white sex bias and a possible Sephardic contribution among the founders of a population in northwest Colombia. Am J Hum Genet 67(5): 1287-1295.

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