Yoruba in Ibadan, Nigeria [YRI]

The biomaterials currently available for this population are shown in the table below:

Population Yoruba in Ibadan, Nigeria [YRI]
Microtiter Plates HAPMAPPT03
Individual DNA Samples 229
Individual Cell Cultures 229

Population Description

Principal Investigators for Community Engagement and Sample Collection:
Charles Rotimi, Howard University, Washington, DC
Clement Adebamowo, University of Ibadan, Ibadan, Nigeria

These cell lines and DNA samples were prepared from blood samples collected in a particular community in Ibadan, Nigeria. All of the samples are from parent-adult child trios. All parents in the trios identified themselves as having four Yoruba grandparents.

It is important to include a reference to "Ibadan, Nigeria" when describing the source of these samples. Including the name of the city and the country where these samples were collected reinforces the point that the sample set, while not genetically "atypical", does not necessarily represent all Yoruba people, whose population history is complex. The population should not be described merely as "African", "Sub-Saharan African", "West African", or "Nigerian", since each of those designators encompasses many populations with different geographic ancestries.

After the complete descriptor “Yoruba in Ibadan, Nigeria” has been provided, it is acceptable to use the shorthand label “Yoruba” or the abbreviation “YRI” in the remainder of the article or presentation. However, the full descriptor for each population should be provided before the shorthand labels are used; this will help to avoid the risks associated with over-generalization of findings.

It may be scientifically appropriate to pool data from these samples with data from other ancestrally related groups, when the data show that the groups have similar allele frequencies. If the groups all have African ancestry, the designation "African ancestry" (abbreviation: AFA) to describe the combined analysis panel is recommended. If only groups very closely related to the Yoruba have similar allele frequencies, then another abbreviation may need to be used.

Note that the adjective form is "Yoruba", as in "the Yoruba samples", not "Yoruban". The accent is on the first syllable (YOR-u-ba).

The Community Advisory Group (CAG) set up in the YRI community to monitor future uses of the YRI samples has established a website (http://www.westafricanbioethics.net/aba-alamu/).

Additional guidance about how to refer to the populations can be found at Guidelines for Referring to the Populations in Publications and Presentations.

Policies and Guidelines