HAPMAPV12
HUMAN VARIATION PANEL
Description:
INTERNATIONAL HAPMAP PROJECT - LUHYA FROM WEBUYE, KENYA
Aliquot Size:
50 µg each
Sex:
Males: 45 Females: 45
Brief Description:
These cell lines and DNA samples were prepared from blood samples collected from unrelated individuals from the Luhya people from Webuye, Kenya.Ninety of these samples (45 males and 45 females) have been included in a panel designated as the HAPMAPV12 panel.
| Prescott NJ, Dominy KM, Kubo M, Lewis CM, Fisher SA, Redon R, Huang N, Stranger BE, Blaszczyk K, Hudspith B, Parkes G, Hosono N, Yamazaki K, Onnie CM, Forbes A, Dermitzakis ET, Nakamura Y, Mansfield JC, Sanderson J, Hurles ME, Roberts RG, Mathew CG, Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease Human molecular genetics19:1828-39 2010 |
| PubMed ID: 20106866 |
| |
| Pemberton, Trevor J., Wang, Chaolong, Li, Jun Z., and Rosenberg, Noah A., Inference of unexpected genetic relatedness among individuals in HapMap phase III Am J Hum Genet87:457-464 2010 |
| PubMed ID: 20869033 |
| |
| Manolio TA, Brooks LD, Collins FS, A HapMap harvest of insights into the genetics of common disease The Journal of clinical investigation118:1590-605 2008 |
| PubMed ID: 18451988 |
| |
| Yngvadottir B, Xue Y, Searle S, Hunt S, Delgado M, Morrison J, Whittaker P, Deloukas P, Tyler-Smith C, A genome-wide survey of the prevalence and evolutionary forces acting on human nonsense SNPs American journal of human genetics84:224-34 2008 |
| PubMed ID: 19200524 |
| |
| Xu Y, Xue Y, Asan Y, Daly A, Wu L, Tyler-Smith C, Variation of the oxytocin/neurophysin I (OXT) gene in four human populations Journal of human genetics53:637-43 2007 |
| PubMed ID: 18566739 |
| |
| Florez JC, Wiltshire S, Agapakis CM, Burtt NP, de Bakker PI, Almgren P, Bengtsson Bostrom K, Tuomi T, Gaudet D, Daly MJ, Hirschhorn JN, McCarthy MI, Altshuler D, Groop L, High-density haplotype structure and association testing of the insulin-degrading enzyme (IDE) gene with type 2 diabetes in 4,206 people. Diabetes55(1):128-35 2006 |
| PubMed ID: 16380485 |
| |
| Plenge R, Rioux JD, Identifying susceptibility genes for immunological disorders: patterns, power, and proof Immunological reviews210:40-51 2006 |
| PubMed ID: 16623763 |
| |
| Spinola M, Meyer P, Kammerer S, Falvella FS, Boettger MB, Hoyal CR, Pignatiello C, Fischer R, Roth RB, Pastorino U, Haeussinger K, Nelson MR, Dierkesmann R, Dragani TA, Braun A, Association of the PDCD5 locus with lung cancer risk and prognosis in smokers Journal of clinical oncology : official journal of the American Society of Clinical Oncology24:1672-8 2006 |
| PubMed ID: 16549820 |
| |
| Sun MW, Lee JY, de Bakker PI, Burtt NP, Almgren P, Råstam L, Tuomi T, Gaudet D, Daly MJ, Hirschhorn JN, Altshuler D, Groop L, Florez JC, Haplotype structures and large-scale association testing of the 5' AMP-activated protein kinase genes PRKAA2, PRKAB1, and PRKAB2 [corrected] with type 2 diabetes Diabetes55:849-55 2006 |
| PubMed ID: 16505254 |
| |
| Weigmann K, Racial medicine: here to stay? The success of the International HapMap Project and other initiatives may help to overcome racial profiling in medicine, but old habits die hard EMBO reports7:246-9 2006 |
| PubMed ID: 16607392 |
| |
| Williams NM, Green EK, Macgregor S, Dwyer S, Norton N, Williams H, Raybould R, Grozeva D, Hamshere M, Zammit S, Jones L, Cardno A, Kirov G, Jones I, O'Donovan MC, Owen MJ, Craddock N, Variation at the DAOA/G30 locus influences susceptibility to major mood episodes but not psychosis in schizophrenia and bipolar disorder Archives of general psychiatry63:366-73 2006 |
| PubMed ID: 16585465 |
| |
| O'Shaughnessy KM, HapMap, pharmacogenomics, and the goal of personalized prescribing British journal of clinical pharmacology61:783-6 2006 |
| PubMed ID: 16722846 |
| |
| Andrulionyte L, Peltola P, Chiasson JL, Laakso M, STOP-NIDDM Study Group M, Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A and the Pro12Ala substitution of PPARG2 predict the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial Diabetes55:2148-52 2006 |
| PubMed ID: 16804087 |
| |
| Newman TL, Rieder MJ, Morrison VA, Sharp AJ, Smith JD, Sprague LJ, Kaul R, Carlson CS, Olson MV, Nickerson DA, Eichler EE, High-throughput genotyping of intermediate-size structural variation Human molecular genetics15:1159-67 2006 |
| PubMed ID: 16497726 |
| |
| Pastinen T, Ge B, Hudson TJ, Influence of human genome polymorphism on gene expression Human molecular genetics15 Spec No 1:R9-16 2006 |
| PubMed ID: 16651375 |
| |
| Yu Y, Panhuysen C, Kranzler HR, Hesselbrock V, Rounsaville B, Weiss R, Brady K, Farrer LA, Gelernter J, Intronic variants in the dopa decarboxylase (DDC) gene are associated with smoking behavior in European-Americans and African-Americans Human molecular genetics15:2192-9 2006 |
| PubMed ID: 16740595 |
| |
| Sabeti PC, Schaffner SF, Fry B, Lohmueller J, Varilly P, Shamovsky O, Palma A, Mikkelsen TS, Altshuler D, Lander ES, Positive natural selection in the human lineage Science312:1614-20 2006 |
| PubMed ID: 16778047 |
| |
| Pe'er I, de Bakker PI, Maller J, Yelensky R, Altshuler D, Daly MJ, Evaluating and improving power in whole-genome association studies using fixed marker sets Nature genetics38:663-7 2006 |
| PubMed ID: 16715096 |
| |
| Macgregor S, Visscher PM, Montgomery G, Analysis of pooled DNA samples on high density arrays without prior knowledge of differential hybridization rates Nucleic acids research34:e55 2006 |
| PubMed ID: 16627870 |
| |
| Nakatani N, Hattori E, Ohnishi T, Dean B, Iwayama Y, Matsumoto I, Kato T, Osumi N, Higuchi T, Niwa S, Yoshikawa T, Genome-wide expression analysis detects eight genes with robust alterations specific to bipolar I disorder: relevance to neuronal network perturbation Human molecular genetics15:1949-62 2006 |
| PubMed ID: 16687443 |
| |
| Min JL, Meulenbelt I, Riyazi N, Kloppenburg M, Houwing-Duistermaat JJ, Seymour AB, van Duijn CM, Slagboom PE, Association of matrilin-3 polymorphisms with spinal disc degeneration and osteoarthritis of the first carpometacarpal joint of the hand Annals of the rheumatic diseases65:1060-6 2006 |
| PubMed ID: 16396979 |
| |
| Carlson CS, Agnosticism and equity in genome-wide association studies Nature genetics38:605-6 2006 |
| PubMed ID: 16736010 |
| |
| Barrett JC, Cardon LR, Evaluating coverage of genome-wide association studies Nature genetics38:659-62 2006 |
| PubMed ID: 16715099 |
| |
| Arking DE, Pfeufer A, Post W, Kao WH, Newton-Cheh C, Ikeda M, West K, Kashuk C, Akyol M, Perz S, Jalilzadeh S, Illig T, Gieger C, Guo CY, Larson MG, Wichmann HE, Marbán E, O'Donnell CJ, Hirschhorn JN, Kääb S, Spooner PM, Meitinger T, Chakravarti A, A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization Nature genetics38:644-51 2006 |
| PubMed ID: 16648850 |
| |
| Gunderson KL, Kuhn KM, Steemers FJ, Ng P, Murray SS, Shen R, Whole-genome genotyping of haplotype tag single nucleotide polymorphisms Pharmacogenomics7:641-8 2006 |
| PubMed ID: 16768648 |
| |
| García-Martín E, Martínez C, Ladero JM, Agúndez JA, Interethnic and intraethnic variability of CYP2C8 and CYP2C9 polymorphisms in healthy individuals Molecular diagnosis & therapy10:29-40 2006 |
| PubMed ID: 16646575 |
| |
| Arnold PD, Sicard T, Burroughs E, Richter MA, Kennedy JL, Glutamate transporter gene SLC1A1 associated with obsessive-compulsive disorder Archives of general psychiatry63:769-76 2006 |
| PubMed ID: 16818866 |
| |
| Iwamoto T, Ikari K, Nakamura T, Kuwahara M, Toyama Y, Tomatsu T, Momohara S, Kamatani N, Association between PADI4 and rheumatoid arthritis: a meta-analysis Rheumatology (Oxford, England)45:804-7 2006 |
| PubMed ID: 16449362 |
| |
| Kathiresan S, Yang Q, Larson MG, Camargo AL, Tofler GH, Hirschhorn JN, Gabriel SB, O'Donnell CJ, Common genetic variation in five thrombosis genes and relations to plasma hemostatic protein level and cardiovascular disease risk Arteriosclerosis, thrombosis, and vascular biology26:1405-12 2006 |
| PubMed ID: 16614319 |
| |
| Lim JE, Papp A, Pinsonneault J, Sadée W, Saffen D, Allelic expression of serotonin transporter (SERT) mRNA in human pons: lack of correlation with the polymorphism SERTLPR Molecular psychiatry11:649-62 2006 |
| PubMed ID: 16432527 |
| |
| Marchini J, Cutler D, Patterson N, Stephens M, Eskin E, Halperin E, Lin S, Qin ZS, Munro HM, Abecasis GR, Donnelly P; International HapMap Consortium., A comparison of phasing algorithms for trios and unrelated individuals. Am J Hum Genet78(3):437-50 2006 |
| PubMed ID: 16465620 |
| |
| Greenawalt DM, Cui X, Wu Y, Lin Y, Wang HY, Luo M, Tereshchenko IV, Hu G, Li JY, Chu Y, Azaro MA, Decoste CJ, Chimge NO, Gao R, Shen L, Shih WJ, Lange K, Li H, Strong correlation between meiotic crossovers and haplotype structure in a 2.5-Mb region on the long arm of chromosome 21. Genome Res16(2):208-14 2006 |
| PubMed ID: 16385099 |
| |
| Ribas G, Gonzalez-Neira A, Salas A, Milne RL, Vega A, Carracedo B, Gonzalez E, Barroso E, Fernandez LP, Yankilevich P, Robledo M, Carracedo A, Benitez J., Evaluating HapMap SNP data transferability in a large-scale genotyping project involving 175 cancer-associated genes. Hum Genet118(6):669-79 2006 |
| PubMed ID: 16323010 |
| |
| Stankovich J, Cox CJ, Tan RB, Montgomery DS, Huxtable SJ, Rubio JP, Ehm MG, Johnson L, Butzkueven H, Kilpatrick TJ, Speed TP, Roses AD, Bahlo M, Foote SJ, On the utility of data from the International HapMap Project for Australian association studies. Hum Genet119(1-2):220-2 2006 |
| PubMed ID: 16404587 |
| |
| Steemers FJ, Chang W, Lee G, Barker DL, Shen R, Gunderson KL, Whole-genome genotyping with the single-base extension assay. Nat Methods3(1):31-3 2006 |
| PubMed ID: 16369550 |
| |
| Conrad DF, Andrews TD, Carter NP, Hurles ME, Pritchard JK, A high-resolution survey of deletion polymorphism in the human genome. Nat Genet38(1):75-81 2006 |
| PubMed ID: 16327808 |
| |
| Helgadottir A, Manolescu A, Helgason A, Thorleifsson G, Thorsteinsdottir U, Gudbjartsson DF, Gretarsdottir S, Magnusson KP, Gudmundsson G, Hicks A, Jonsson T, Grant SF, Sainz J, O'Brien SJ, Sveinbjornsdottir S, Valdimarsson EM, Matthiasson SE, Levey AI, Abramson JL, Reilly MP, Vaccarino V, Wolfe ML, Gudnason V, Quyyumi AA, Topol EJ, Rader DJ, Thorgeirsson G, Gulcher JR, Hakonarson H, Kong A, Stefansson K, A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction. Nat Genet38(1):68-74 2006 |
| PubMed ID: 16282974 |
| |
| Silberberg G, Darvasi A, Pinkas-Kramarski R, Navon R, The involvement of ErbB4 with schizophrenia: association and expression studies. Am J Med Genet B Neuropsychiatr Genet141(2):142-8 2006 |
| PubMed ID: 16402353 |
| |
| Garcia-Barcelo M, So MT, Lau DK, Leon TY, Yuan ZW, Cai WS, Lui VC, Fu M, Herbrick JA, Gutter E, Proud V, Li L, Pierre-Louis J, Aleck K, van Heurn E, Belloni E, Scherer SW, Tam PK, Population differences in the polyalanine domain and 6 new mutations in HLXB9 in patients with Currarino syndrome. Clin Chem52(1):46-52 2006 |
| PubMed ID: 16254195 |
| |
| Ireland J, Carlton VE, Falkowski M, Moorhead M, Tran K, Useche F, Hardenbol P, Erbilgin A, Fitzgerald R, Willis TD, Faham M, Large-scale characterization of public database SNPs causing non-synonymous changes in three ethnic groups. Hum Genet119(1-2):75-83 2006 |
| PubMed ID: 16391945 |
| |
| McCarroll SA, Hadnott TN, Perry GH, Sabeti PC, Zody MC, Barrett JC, Dallaire S, Gabriel SB, Lee C, Daly MJ, Altshuler DM; International HapMap Consortium, Common deletion polymorphisms in the human genome. Nat Genet38(1):86-92 2006 |
| PubMed ID: 16468122 |
| |
| Taylor JA, Xu ZL, Kaplan NL, Morris RW, How well do HapMap haplotypes identify common haplotypes of genes? A comparison with haplotypes of 334 genes resequenced in the environmental genome project. Cancer Epidemiol Biomarkers Prev15(1):133-7 2006 |
| PubMed ID: 16434598 |
| |
| Zhu H, Yang W, Lu W, Zhang J, Shaw GM, Lammer EJ, Finnell RH, A known functional polymorphism (Ile120Val) of the human PCMT1 gene and risk of spina bifida. Mol Genet Metab87(1):66-70 2006 |
| PubMed ID: 16256389 |
| |
| Auro K, Komulainen K, Alanne M, Silander K, Peltonen L, Perola M, Salomaa V, Thrombomodulin gene polymorphisms and haplotypes and the risk of cardiovascular events: a prospective follow-up study Arteriosclerosis, thrombosis, and vascular biology26:942-7 2006 |
| PubMed ID: 16456088 |
| |
| Herbert A, Gerry NP, McQueen MB, Heid IM, Pfeufer A, Illig T, Wichmann HE, Meitinger T, Hunter D, Hu FB, Colditz G, Hinney A, Hebebrand J, Koberwitz K, Zhu X, Cooper R, Ardlie K, Lyon H, Hirschhorn JN, Laird NM, Lenburg ME, Lange C, Christman MF, A common genetic variant is associated with adult and childhood obesity Science312:279-83 2006 |
| PubMed ID: 16614226 |
| |
| Kathiresan S, Larson MG, Vasan RS, Guo CY, Gona P, Keaney JF, Wilson PW, Newton-Cheh C, Musone SL, Camargo AL, Drake JA, Levy D, O'Donnell CJ, Hirschhorn JN, Benjamin EJ, Contribution of clinical correlates and 13 C-reactive protein gene polymorphisms to interindividual variability in serum C-reactive protein level Circulation113:1415-23 2006 |
| PubMed ID: 16534007 |
| |
| Siitonen N, Pulkkinen L, Mager U, Lindström J, Eriksson JG, Valle TT, Hämäläinen H, Ilanne-Parikka P, Keinänen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M, Association of sequence variations in the gene encoding adiponectin receptor 1 (ADIPOR1) with body size and insulin levels The Finnish Diabetes Prevention Study Diabetologia49:1795-805 2006 |
| PubMed ID: 16724230 |
| |
| Shimizu H, Iwayama Y, Yamada K, Toyota T, Minabe Y, Nakamura K, Nakajima M, Hattori E, Mori N, Osumi N, Yoshikawa T, Genetic and expression analyses of the STOP (MAP6) gene in schizophrenia Schizophrenia research84:244-52 2005 |
| PubMed ID: 16624526 |
| |
| Lerner-Ellis JP, Gradinger AB, Watkins D, Tirone JC, Villeneuve A, Dobson CM, Montpetit A, Lepage P, Gravel RA, Rosenblatt DS, Mutation and biochemical analysis of patients belonging to the cblB complementation class of vitamin B12-dependent methylmalonic aciduria Molecular genetics and metabolism87:219-25 2005 |
| PubMed ID: 16410054 |
| |
| Jorde LB, Evolution. Where we're hot, they're not. Science308(5718):60-2 2005 |
| PubMed ID: 15802591 |
| |
| Kammerer S, Roth RB, Hoyal CR, Reneland R, Marnellos G, Kiechle M, Schwarz-Boeger U, Griffiths LR, Ebner F, Rehbock J, Cantor CR, Nelson MR, Braun A, Association of the NuMA region on chromosome 11q13 with breast cancer susceptibility. Proc Natl Acad Sci U S A102(6):2004-9 2005 |
| PubMed ID: 15684076 |
| |
| Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, Haynes C, Henning AK, SanGiovanni JP, Mane SM, Mayne ST, Bracken MB, Ferris FL, Ott J, Barnstable C, Hoh J, Complement factor H polymorphism in age-related macular degeneration. Science308(5720):385-9 2005 |
| PubMed ID: 15761122 |
| |
| Qu H, Tessier MC, Hudson TJ, Polychronakos C, Confirmation of the association of the R620W polymorphism in the protein tyrosine phosphatase PTPN22 with type 1 diabetes in a family based study. J Med Genet42(3):266-70 2005 |
| PubMed ID: 15744042 |
| |
| Altshuler D, Brooks LD, Chakravarti A, Collins FS, Daly MJ, Donnelly P; International HapMap Consortium, A haplotype map of the human genome. Nature437(7063):1299-320 2005 |
| PubMed ID: 16255080 |
| |
| Goldstein DB, Cavalleri GL, Genomics: understanding human diversity. Nature437(7063):1241-2 2005 |
| PubMed ID: 16251937 |
| |
| Thorisson GA, Smith AV, Krishnan L, Stein LD, The International HapMap Project Web site. Genome Res15(11):1592-3 2005 |
| PubMed ID: 16251469 |
| |
| Clark AG, Hubisz MJ, Bustamante CD, Williamson SH, Nielsen R, Ascertainment bias in studies of human genome-wide polymorphism. Genome Res15(11):1496-502 2005 |
| PubMed ID: 16251459 |
| |
| de Bakker PI, Yelensky R, Pe'er I, Gabriel SB, Daly MJ, Altshuler D, Efficiency and power in genetic association studies. Nat Genet37(11):1217-23 2005 |
| PubMed ID: 16244653 |
| |
| Ge B, Gurd S, Gaudin T, Dore C, Lepage P, Harmsen E, Hudson TJ, Pastinen T, Survey of allelic expression using EST mining. Genome Res15(11):1584-91 2005 |
| PubMed ID: 16251468 |
| |
| Geisen C, Watzka M, Sittinger K, Steffens M, Daugela L, Seifried E, Muller CR, Wienker TF, Oldenburg J, VKORC1 haplotypes and their impact on the inter-individual and inter-ethnical variability of oral anticoagulation. Thromb Haemost94(4):773-9 2005 |
| PubMed ID: 16270629 |
| |
| Nielsen R, Williamson S, Kim Y, Hubisz MJ, Clark AG, Bustamante C, Genomic scans for selective sweeps using SNP data. Genome Res15(11):1566-75 2005 |
| PubMed ID: 16251466 |
| |
| Smith AV, Thomas DJ, Munro HM, Abecasis GR, Sequence features in regions of weak and strong linkage disequilibrium. Genome Res15(11):1519-34 2005 |
| PubMed ID: 16251462 |
| |
| Weir BS, Cardon LR, Anderson AD, Nielsen DM, Hill WG, Measures of human population structure show heterogeneity among genomic regions. Genome Res15(11):1468-76 2005 |
| PubMed ID: 16251456 |
| |
| Andrawiss M, First phase of HapMap project already helping drug discovery. Nat Rev Drug Discov4(12):947 2005 |
| PubMed ID: 16370072 |
| |
| Hamilton G, Samedi F, Knight J, Archer N, Foy C, Walter S, Turic D, Jehu L, Moore P, Hollingworth P, O'Donovan MC, Williams J, Owen MJ, Lovestone S, Powell JF, Polymorphisms in the phosphate and tensin homolog gene are not associated with late-onset Alzheimer's disease Neuroscience letters401:77-80 2005 |
| PubMed ID: 16574322 |
| |
| Hanchard N, Diakite M, Koch O, Keating B, Pinder M, Jallow M, Sisay-Joof F, Nijnik A, Wilson J, Udalova I, Kwiatkowski D, Rockett K, Implications of inter-population linkage disequilibrium patterns on the approach to a disease association study in the human MHC class III Immunogenetics58:465-70 2005 |
| PubMed ID: 16738941 |
| |
| Fry AE, Trafford CJ, Kimber MA, Chan MS, Rockett KA, Kwiatkowski DP, Haplotype homozygosity and derived alleles in the human genome American journal of human genetics78:1053-9 2005 |
| PubMed ID: 16685655 |
| |
| Soyal S, Krempler F, Oberkofler H, Patsch W, PGC-1alpha: a potent transcriptional cofactor involved in the pathogenesis of type 2 diabetes Diabetologia49:1477-88 2005 |
| PubMed ID: 16752166 |
| |
| Pe'er I, Chretien YR, de Bakker PI, Barrett JC, Daly MJ, Altshuler DM, Biases and reconciliation in estimates of linkage disequilibrium in the human genome American journal of human genetics78:588-603 2005 |
| PubMed ID: 16532390 |
| |
| Evans PD, Vallender EJ, Lahn BT, Molecular evolution of the brain size regulator genes CDK5RAP2 and CENPJ Gene375:75-9 2005 |
| PubMed ID: 16631324 |
| |
| Zhang Y, Niu T, Liu JS, A coalescence-guided hierarchical Bayesian method for haplotype inference American journal of human genetics79:313-22 2005 |
| PubMed ID: 16826521 |
| |
| Pandit B, Ahn GS, Hazard SE, Gordon D, Patel SB, A detailed Hapmap of the Sitosterolemia locus spanning 69 kb; differences between Caucasians and African-Americans BMC medical genetics [electronic resource]7:13 2005 |
| PubMed ID: 16507104 |
| |
| Xue Y, Daly A, Yngvadottir B, Liu M, Coop G, Kim Y, Sabeti P, Chen Y, Stalker J, Huckle E, Burton J, Leonard S, Rogers J, Tyler-Smith C, Spread of an inactive form of caspase-12 in humans is due to recent positive selection American journal of human genetics78:659-70 2005 |
| PubMed ID: 16532395 |
| |
| Foster, M., Genetics and social identity after the HapMap. Nature Rev Genet6:1 2005 |
| PubMed ID: 16532395 |
|
|