Coriell Institute

NDPT087 96 WELL PLATE OF DNA SAMPLES

Description: YOUNG ONSET PARKINSON'S PANEL: AFFECTED INDIVIDUALS

Aliquot Size: 5 µg each

Sex: Males: 51 Females: 39

Brief Description: This panel contains 5 micrograms of DNA from 90 unique and unrelated White individuals with young onset Parkinson's disease (YOPD). These include 51 males and 39 females from North America. The age of PD onset ranges from 7 years to 40 years. All subjects meet the UK Brain Bank Criteria for idiopathic Parkinson's disease [Hughes et al. JNNP 55:181-184 (1992)]. None have apparent Mendelian inheritance of PD. A more detailed description is also available. NDPT087 replaces NPDT014 and it has all of the same samples, except: ND00887 was removed because it is from the same subject as ND02272 (present on this panel), ND00072 was removed because it was discovered to have a known mutation in LRRK2 (IVS20+4DELGT), and ND09440 replaces ND04741.
Plate Layout: The specific position on the plates has been optimized to reduce any possible errors in sample identity during the genotyping process.



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