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dbGaP Study Description: National Institute of Neurological Disorders and Stroke (NINDS) Repository Neurologically Normal Control Collection
dbGaP Study Detail Description: The NINDS repository (http://ccr.coriell.org/ninds/) was established in October 2001 with the goal of developing standardized, broadly useful diagnostic and other clinical data, as well as a collection of DNA and cell line samples to further advance gene discovery of neurological disorders. All samples and both phenotypic and genotypic data are available to the research community including academic and industry scientists. A set of samples from individuals who do not have neurological disease was felt to be essential to allow gene discovery in neurological disorders to proceed. Towards this goal, the NINDS has and is collecting samples and phenotypic data on neurologically normal individuals. The data being collected includes demographic, ethnic, and exclusion of neurological disease information. Variables were measured using the Control Clinical Data Elements form. As of June 2007, there are a total of 2157 publicly available and an additional >2000 which will be added to the publicly available biomaterials collection shortly. Blood samples were drawn from neurologically normal, unrelated, individuals at many different sites. Spouses, convenience controls, and population controls were all included in this collection. Each participant underwent a detailed medical history interview and had no family history on specific query of Alzheimer's disease, amyotrophic lateral sclerosis, ataxia, autism, bipolar disorder, brain aneurysm, dementia, dystonia, or Parkinson's disease. Folstein Mini-mental state examination scores ranged from 26-30 and are available on a subset of individuals. All participants were interviewed for family history in detail and specifically had no first degree relative with any of the following: amyotrophic lateral sclerosis, ataxia, autism, brain aneurysm, dystonia, Parkinson's disease, and schizophrenia.
Records Return:  (2686) Show
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Catalog IDDiagnosisCell TypeRaceAgeGenderAffected
ND00001POPULATION/CONVENIENCE CONTROLB-LymphocyteCaucasian74 YRMaleNo
ND00005POPULATION/CONVENIENCE CONTROLB-LymphocyteUnknown29 YRFemaleNo
ND00009POPULATION/CONVENIENCE CONTROLB-LymphocyteCaucasian60 YRMaleNo
ND00011POPULATION/CONVENIENCE CONTROLB-LymphocyteCaucasian75 YRFemaleNo
ND00016POPULATION/CONVENIENCE CONTROLB-LymphocyteCaucasian53 YRFemaleNo
ND00022POPULATION/CONVENIENCE CONTROLB-LymphocyteCaucasian72 YRMaleNo
ND00024POPULATION/CONVENIENCE CONTROLB-LymphocyteCaucasian49 YRFemaleNo
ND00025POPULATION/CONVENIENCE CONTROLB-LymphocyteCaucasian56 YRFemaleNo
ND00044POPULATION/CONVENIENCE CONTROLB-LymphocyteCaucasian78 YRFemaleNo
ND00049POPULATION/CONVENIENCE CONTROLB-LymphocyteCaucasian74 YRMaleNo
ND00051POPULATION/CONVENIENCE CONTROLB-LymphocyteCaucasian67 YRFemaleNo
ND00052POPULATION/CONVENIENCE CONTROLB-LymphocyteCaucasian76 YRFemaleNo
ND00053POPULATION/CONVENIENCE CONTROLB-LymphocyteCaucasian76 YRFemaleNo
ND00056POPULATION/CONVENIENCE CONTROLB-LymphocyteCaucasian44 YRFemaleNo
ND00062POPULATION/CONVENIENCE CONTROLB-LymphocyteCaucasian69 YRMaleNo
ND00063POPULATION/CONVENIENCE CONTROLB-LymphocyteCaucasian49 YRFemaleNo
ND00065POPULATION/CONVENIENCE CONTROLB-LymphocyteCaucasian38 YRFemaleNo
ND00066POPULATION/CONVENIENCE CONTROLB-LymphocyteCaucasian42 YRMaleNo
ND00068POPULATION/CONVENIENCE CONTROLB-LymphocyteCaucasian72 YRFemaleNo
ND00069POPULATION/CONVENIENCE CONTROLB-LymphocyteCaucasian56 YRMaleNo