Genomic, Epigenomic and Multiomics Services

At the Coriell Institute, our team of technical experts ensures meticulous handling of your samples, from nucleic acid extraction to high-throughput sequencing, bioinformatics analysis, and customized data reporting tailored to your specific needs.

Genomics Services

We offer a range of DNA and RNA sequencing services, including:

  • Whole genome sequencing (WGS)– Comprehensive sequencing of the entire genome.
  • Whole exome sequencing (WES)– Focused on coding genes for targeted insights.
  • Targeted gene sequencing– Customized to analyze specific genes of interest.
  • RNA sequencing (RNA-seq)– Profiling gene expression, noncoding RNA, and repetitive elements, with in-depth data analysis and reporting.

Epigenomics Services

We provide a variety of cutting-edge epigenomic analyses, including:

  • DNA methylation sequencing– Genome-wide coverage of millions of CpG sites or targeted methylation sequencing for specific genes.
  • Chromatin accessibility analysis (ATAC-seq)– Genome-wide profiling of open chromatin regions.
  • Histone modification analysis (CUT&Tag)– Identifying active and repressive chromatin states.

Single-Cell and Multiomics Services

Beyond bulk population analysis, we offer advancedsingle-cell sequencingto reveal unique cellular subpopulations and their gene expression patterns. Our services include:

  • Single-cell RNA sequencing (scRNA-seq)– Profiling gene expression at the single-cell level.
  • Single-cell ATAC sequencing (scATAC-seq)– Mapping chromatin accessibility within individual cells.
  • Single-cell multiome sequencing– Simultaneously analyzing gene expression and chromatin accessibility across thousands of individual cells.

Whether you need comprehensive sequencing, in-depth bioinformatics analysis, or customized data reporting,Coriell is your trusted partner in cutting-edge genomics and epigenomics research.