Services at Coriell

Having set the gold standard for biobanking around to globe, we at Coriell are experts in every step of the pipeline. We establish immortalized cell lines, run those lines through extensive quality control protocols, extract DNA from them, reprogram these cells into state-of-the-art induced pluripotent stem cells, freeze them and store them in our long term cryogenic storage facility, and we know how to distribute these precious materials to scienists around the world. 

As dedicated researchers, we also have to talent and know-how to assist on the analtyical side as well. We lead the drive in personalized medicine with the Coriell Personalized Medicine Collaborative 

We'd like to help you in your lab. Take a look at the services we offer below. 

And if there's something your team needs assistance with and you think we might be able to help, please drop us a line. We provide custom lab solutions as well.

Stem Cells

Biobanking and Distribution

Stem Cell Core Services

  • Reprogramming
  • Characterization
  • Differentiated Cell Lines
  • Expansion and Banking
  • iPSC-derived Organoids

Key iPSC Quality Control Assays

  • Post-thaw viability and growth rate
  • Sterility
  • Mycoplasma
  • Identity match (DNA fingerprinting)
  • G-banded karyotype
  • Affymetrix Genome-Wide Human SNP Array 6.0
  • Confirmation of integration-free reprogramming
  • Pluripotency
  • Tri-lineage differentiation potential

Biobanking

  • Establishment of public and private repositories and independent biobanks
  • Banking, cryopreservation and fail-safe storage of cell lines, DNA, and other biomaterials
  • Repository Information Management Systems
  • Online catalogs with annotation of samples
  • Collection and distribution systems, online tracking of all shipments
  • Controlled-access to samples and associated data
  • Redundant backup generators

Research Support Services

  • Primary and transformed cell lines
  • DNA and RNA isolation and quality control
  • Data analysis
  • Designing a study that includes microarray
  • Quality assurance certification
  • Customized project reports
  • Ensuring your study design accounts for participant confidentiality
  • Advice on human subject research and Institutional Review Board approval
  • Shipping of biospecimens domestically and internationally
  • Controlled-access to samples and associated data
  • Redundant backup generators

Collection Kits

Cell and Molecular Analysis

Customized Experimental Design and Research Solutions

Genomic and Epigenomic Services

Epigenetics

  • Genome-wide DNA methylation analysis
  • Gene-specific DNA methylation analysis
  • Chromatin accessibility analysis (ATAC-seq) for mapping of opened and closed chromatin
  • Chromatin immunoprecipitation (ChIP-seq) for histone marks and DNA-binding proteins

Bioinformatic analyses of next generation sequencing data

Single cell RNA-sequencing

Nucleic Acid Isolation and Quality Control

  • DNA and RNA Isolation
  • Customized Product Preparations
  • Identity Testing
  • Species Identity Testing
  • Sex Determination Assay
  • Verification of Family Pedigrees
  • Mycoplasma Screening

Biomarkers

  • Receipt and storage of a variety of samples at optimal temperature
  • Processing of samples to yield DNA, RNA
  • Reporting of life-cycle of samples; enterprise-level LIMS
  • Hemoglobin assays to assess quality of serum, plasma, and cerebrospinal fluid
  • Development of additional biomarker assays and Quality Control
  • Redundant backup generators
  • Controlled access to samples and associated data

Cell Culture 

  • Establishment of cell lines from tissue and blood
  • Fibroblasts, endothelial, smooth muscle, and epithelial cell cultures from biopsies
  • Epstein-Barr virus transformed lymphoblast lines
  • Isolation and cryopreservation of buffy coats
  • Expansion of cell lines for distribution, stock maintenance, molecular and cytogenetic analysis
  • Quality control assessment of existing cell lines
  • Detection of mycoplasma contamination
  • Fail-safe storage of plasma, serum, and other biosamples
  • Controlled-access to samples and associated data
  • Redundant backup generators
  • Custom cell banking

Research and Development Models

Interested in working with us? Click the button below or call us at (800) 752-3805 (US) or (856) 757-4848 (World) to learn more about how we can help you.


Tell us about your needs


The Coriell Institute for Medical Research’s quality management system has been certified to the ISO 9001:2015 standard.