NIGMS

Human Genetic Cell Repository


The NIGMS Human Genetic Cell Repository, sponsored by the National Institute of General Medical Sciences, provides scientists around the world with resources for cell and genetic research. Established in 1972 at the Coriell Institute for Medical Research, the NIGMS Repository contains more than 11,700 cell lines, primarily fibroblasts and transformed lymphoblasts, and more than 6,300 DNA samples. Currently, the NIGMS HGCR catalog also contains nearly 60 iPSC lines. Repository samples represent a variety of disease states, chromosomal abnormalities, apparently healthy individuals and many distinct human populations.

Data on this website and information derived from the samples in the NIGMS Repository may not be used to determine the identity of any individual who provided a sample. Sample data available in the NIGMS Repository regarding race, ethnicity, and/or ancestry is self-reported information provided by sample submitters. Coriell has not verified the accuracy of such data. Please direct any questions about these policies to NIGMS@coriell.org.

NIGMS News

  • Apr 2021

    FFPE Cell Pellet Scrolls Now Available from the NIGMS HGCR

    Formalin-Fixed Paraffin-Embedded (FFPE) scrolls are now available for the cell line GM12878 via Coriell Institute’s online catalog. This product, Repository ID: FF12878, is available as a set of FFPE scrolls of a homogenous cell pellet of GM12878.

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  • Mar 2021

    NIGMS Human Genetic Cell Repository Highlighted on Rare Disease Day

    The NIGMS Human Genetic Cell Repository was featured in a recent event recognizing Rare Disease Day 2021, highlighting the role that patients with heritable diseases play in advancing rare disease research.

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  • Jan 2021

    Characterized Reference Materials Available for Spinal Muscular Atrophy

    Researchers from the Genetic Testing Reference Materials Coordination Program (GeT-RM) have published a study (PMID: 33197628) in collaboration with the NIGMS Repository, to establish genotypic characterizations of high quality reference materials for Spinal Muscular Atrophy (SMA).

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Other News