Human Genetic Cell Repository

The NIGMS Human Genetic Cell Repository, sponsored by the National Institute of General Medical Sciences, provides scientists around the world with resources for cell and genetic research. Established in 1972 at the Coriell Institute for Medical Research, the NIGMS Repository contains more than 11,900 cell lines, primarily fibroblasts and transformed lymphoblasts, and more than 5,900 DNA samples. Currently, the NIGMS HGCR catalog also contains over 85 iPSC lines.

Repository samples represent a variety of disease states, chromosomal abnormalities, apparently healthy individuals, and many distinct human populations. These samples comprise over 1,100 different OMIM diagnoses, and have been referenced in over 6,900 scientific publications.

Data on this website and information derived from the samples in the NIGMS Repository may not be used to determine the identity of any individual who provided a sample. Sample data available in the NIGMS Repository regarding race and/or ethnicity is self-reported information provided by sample submitters. Please direct any questions about these policies to


  • Mar 2023

    Human Genetic Cell Repository Featured on NIGMS Blog

    The National Institute of General Medical Sciences (NIGMS) recently celebrated the 50th anniversary of the Human Genetic Cell Repository (HGCR), housed at the Coriell Institute, in its Biomedical Beat blog where writers shine a light on scientists and research backed by NIGMS.

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  • Feb 2023

    Rare Disease Day: FAQs for Contributing to the NIGMS Human Genetic Cell Repository

    For those affected by a rare disease, there is an accessible way to contribute to the research effort. The Human Genetic Cell Repository (HGCR), sponsored by the National Institute of General Medical Sciences (NIGMS) and hosted at the Coriell Institute, contains many thousands of cell line and DNA samples derived from tissue donations from affected people, allowing researchers to study these diseases and develop new therapies. The collection of samples representing rare diseases is always growing!

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  • Feb 2023

    New iPSC Lines Added in 2022

    Dozens of induced pluripotent stem cell (iPSC) lines were added to the collections in Coriell's care last year. See a full list of new lines here.

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