HAPMAPPT07
96 WELL PLATE OF DNA SAMPLES
Description:
INTERNATIONAL HAPMAP PROJECT - AFRICAN ANCESTRY IN SW USA
Aliquot Size:
50 µg each
Sex:
Males: 41 Females: 49
Brief Description:
The HAPMAPPT07 plate, from People with African Ancestry in the Southwestern United States includes a set of 11 trios, 24 duos and 9 singletons (90 samples). In addition, there are 5 duplicated samples and 1 buffer control. The concentration of each DNA sample to be plated is normalized and then this concentration is verified. The DNA concentration is 250 ng/µl and there are 50 µg of DNA per well. Once all samples are in place, a DNA fingerprint is determined for each sample to verify the identity on the plate. The specific position on the plates has been optimized by NHGRI to reduce any possible errors in sample identity during the genotyping process. The positions of the 5 duplicated samples and 1 buffer control are indicated by gray shading.
Wheeler HE, Gorsic LK, Welsh M, Stark AL, Gamazon ER, Cox NJ, Dolan ME, Genome-wide local ancestry approach identifies genes and variants associated with chemotherapeutic susceptibility in African Americans PloS one6:e21920 2011 |
PubMed ID: 21755009 |
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Pemberton, Trevor J., Wang, Chaolong, Li, Jun Z., and Rosenberg, Noah A., Inference of unexpected genetic relatedness among individuals in HapMap phase III Am J Hum Genet87:457-464 2010 |
PubMed ID: 20869033 |
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Manolio TA, Brooks LD, Collins FS, A HapMap harvest of insights into the genetics of common disease The Journal of clinical investigation118:1590-605 2008 |
PubMed ID: 18451988 |
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O'Shaughnessy KM, HapMap, pharmacogenomics, and the goal of personalized prescribing British journal of clinical pharmacology61:783-6 2006 |
PubMed ID: 16722846 |
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