Genomic and Epigenomic Services

Epigenetics

• Genome-wide DNA methylation analysis: reduced representation bisulfite sequencing (RRBS), whole genome bisulfite sequencing (WGBS), digital restriction enzyme analysis of methylation (DREAM).
• Gene-specific DNA methylation analysis: bisulfite pyrosequencing, bisulfite amplicon sequencing
• Chromatin accessibility analysis (ATAC-seq) for mapping of opened and closed chromatin
• Chromatin immunoprecipitation (ChIP-seq) for histone marks and DNA-binding proteins

Bioinformatic analyses of next generation sequencing data

• DNA: low pass or high coverage genomic sequencing, whole exome sequencing, custom targeted sequencing, amplicon sequencing
• RNA: polyA, random primed, strand-specific sequencing

Single cell RNA-sequencing

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The Coriell Institute for Medical Research’s quality management system has been certified to the ISO 9001:2015 standard.