Description:
TRANSLOCATED CHROMOSOME
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Repository
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NIGMS Human Genetic Cell Repository
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| Subcollection |
Chromosome Abnormalities |
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Cell Type
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Fibroblast
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Transformant
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Untransformed
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Race
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White
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Relation to Proband
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proband
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Confirmation
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Karyotypic analysis after cell line submission to CCR
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ISCN
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45,XY,der(5)(5qter>5p14 ::15q11>15qter),t(9;11)(9qter>9p24:: 11q23>11qter;11pter>11q23::9p24>9pter),-15
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Species
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Homo sapiens
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Common Name
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Human
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Remarks
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| Passage Frozen |
4 |
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| IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin Confirmed by Chromosome Analysis |
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| Cytogenetics |
Chromosome 15: DERIVATIVE CHROMOSOME Aneuploid Segment (-)15pter>15q11 |
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Chromosome 5: DERIVATIVE CHROMOSOME Aneuploid Segment (-)5pter>5p14 |
| Rovigatti U, Watson DK, Yunis JJ, Amplification and rearrangement of Hu-ets-1 in leukemia and lymphoma with involvement of 11q23. Science232:398-400 1986 |
| PubMed ID: 3457468 |
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| Meager A, Graves HE, Shuttleworth J, Zucker N, Interferon production: variation in yields from human cell lines. Infect Immun25:658-63 1979 |
| PubMed ID: 489124 |
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| Slate DL, Ruddle FH, Fibroblast interferon in man is coded by two loci on separate chromosomes. Cell16:171-80 1979 |
| PubMed ID: 84714 |
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| Jackson L, Barr M, Aronson M, Greene AE, Coriell LL, A double translocation culture t(5;15)t(9;11) with partial deletion of the short arm of chromosome 5. Repository identification No. GM-344. Cytogenet Cell Genet15:400-1 1975 |
| PubMed ID: 1225499 |
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| Jackson L, Barr M, A 45,XY,5-15-,t(5q15q) cri-du-chat child. J Med Genet7:161-3 1970 |
| PubMed ID: 5519604 |
| Passage Frozen |
4 |
| Split Ratio |
1:3 |
| Temperature |
37 C |
| Percent CO2 |
5% |
| Medium |
Eagle's Minimum Essential Medium with Earle's salts and non-essential amino acids with 2mM L-glutamine or equivalent |
| Serum |
15% fetal bovine serum Not inactivated |
| Substrate |
None specified |
| Subcultivation Method |
trypsin-EDTA |
| Supplement |
- |
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