Description:
TRANSLOCATED CHROMOSOME
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Repository
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NIGMS Human Genetic Cell Repository
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| Subcollection |
Chromosome Abnormalities |
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Cell Type
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Fibroblast
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Transformant
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Untransformed
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Race
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White
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Family Member
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1
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Relation to Proband
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proband
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Confirmation
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Karyotypic analysis after cell line submission to CCR
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ISCN
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46,XX,t(2;6)(2pter>2q11::6q15>6qter; 6pter>6q15::2q11>2qter)
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Species
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Homo sapiens
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Common Name
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Human
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Remarks
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| Passage Frozen |
4 |
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| IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin Confirmed by Chromosome Analysis |
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| Cytogenetics |
Chromosome 2: TRANSLOCATION Breakpoint 2q11 t(2;6)2q11 |
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Chromosome 6: TRANSLOCATION Breakpoint 6q15 t(2;6)6q15 |
| Remarks |
Same patient as GM02699 |
| Kimura S, Kotani T, McBride OW, Umeki K, Hirai K, Nakayama T, Ohtaki S, Human thyroid peroxidase: complete cDNA and protein sequence, chromosome mapping, and identification of two alternately spliced mRNAs. Proc Natl Acad Sci U S A84:5555-9 1987 |
| PubMed ID: 3475693 |
| |
| McBride OW, Zmudzka BZ, Wilson SH, Chromosomal location of the human gene for DNA polymerase beta. Proc Natl Acad Sci U S A84:503-7 1987 |
| PubMed ID: 3467369 |
| |
| McBride OW, Merry D, Givol D, The gene for human p53 cellular tumor antigen is located on chromosome 17 short arm (17p13). Proc Natl Acad Sci U S A83:130-4 1986 |
| PubMed ID: 3001719 |
| Passage Frozen |
4 |
| Split Ratio |
1:3 |
| Temperature |
37 C |
| Percent CO2 |
5% |
| Medium |
Eagle's Minimum Essential Medium with Earle's salts and non-essential amino acids with 2mM L-glutamine or equivalent |
| Serum |
15% fetal bovine serum Not inactivated |
| Substrate |
None specified |
| Subcultivation Method |
trypsin-EDTA |
| Supplement |
- |
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