GM02669
LCL from B-Lymphocyte
Description:
TRANSLOCATED CHROMOSOME
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Repository
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NIGMS Human Genetic Cell Repository
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| Subcollection |
Chromosome Abnormalities |
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Biopsy Source
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Peripheral vein
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Cell Type
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B-Lymphocyte
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Tissue Type
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Blood
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Transformant
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Epstein-Barr Virus
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Sample Source
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LCL from B-Lymphocyte
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Race
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White
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Relation to Proband
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proband
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Confirmation
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Clinical summary/Case history
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ISCN
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46,XY,t(6;8)(6pter>6q27::8q21>8qter; 8pter>8q21::6q27>6qter)
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Species
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Homo sapiens
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Common Name
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Human
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Remarks
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| IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin Confirmed by Chromosome Analysis |
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| Cytogenetics |
Chromosome 6: TRANSLOCATION Breakpoint 6q27 |
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Chromosome 6: TRANSLOCATION Breakpoint 6q27 t(6;8)6q27 |
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Chromosome 8: TRANSLOCATION Breakpoint 8q21 |
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Chromosome 8: TRANSLOCATION Breakpoint 8q21 t(6;8)8q21 |
| Remarks |
Clinically normal |
| Erikson J, ar-Rushdi A, Drwinga HL, Nowell PC, Croce CM, Transcriptional activation of the translocated c-myc oncogene in burkitt lymphoma. Proc Natl Acad Sci U S A80:820-824 1983 |
| PubMed ID: 6402776 |
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| Nishikura K, ar-Rushdi A, Erikson J, Watt R, Rovera G, Croce CM, Differential expression of the normal and of the translocated human c- myc oncogenes in B cells. Proc Natl Acad Sci U S A80:4822-6 1983 |
| PubMed ID: 6308654 |
| Split Ratio |
1:4 |
| Temperature |
37 C |
| Percent CO2 |
5% |
| Medium |
Roswell Park Memorial Institute Medium 1640 with 2mM L-glutamine or equivalent |
| Serum |
20% fetal bovine serum Not Inactivated |
| Substrate |
None specified |
| Subcultivation Method |
dilution - add fresh medium |
| Supplement |
- |
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