GM04155
LCL from B-Lymphocyte
Description:
ACUTE LYMPHOCYTIC LEUKEMIA
LYMPHOSARCOMA
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Repository
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NIGMS Human Genetic Cell Repository
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| Subcollection |
Heritable Diseases |
| Class |
Heritable Cancer Syndromes and other Cancers |
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Biopsy Source
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Peripheral vein
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Cell Type
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T-Lymphocyte
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Tissue Type
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Blood
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Transformant
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Possibly Human T-cell Leukemia Virus
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Sample Source
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LCL from B-Lymphocyte
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Race
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White
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Family Member
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1
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Relation to Proband
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proband
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Confirmation
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Clinical summary/Case history
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ISCN
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XY
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Species
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Homo sapiens
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Common Name
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Human
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Remarks
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| IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin Confirmed by Chromosome Analysis |
| |
| Remarks |
T cell line CCRF-HSB2; same patient as GM04154B; negative for T cell 65,000 MW glycoprotein, sIg, & Ia(B cell) antigen; all cells nearly diploid with frequent chromosome loss; marker chromosome (13q-?) present in all cells |
| Haataja L, Groffen J, Heisterkamp N, Characterization of RAC3, a novel member of the Rho family. J Biol Chem272:20384-8 1997 |
| PubMed ID: 9252344 |
| |
| Heisterkamp N, Mulder MP, Langeveld A, ten Hoeve J, Wang Z, Roe BA, Groffen J, Localization of the human mitochondrial citrate transporter protein gene to chromosome 22Q11 in the DiGeorge syndrome critical region. Genomics29:451-6 1995 |
| PubMed ID: 8666394 |
| |
| Wellner VP, Anderson ME, Puri RN, Jensen GL, Meister A, Radioprotection by glutathione ester: transport of glutathione ester into human lymphoid cells and fibroblasts. Proc Natl Acad Sci U S A81:4732-5 1984 |
| PubMed ID: 6146978 |
| |
| Shipp MA, Schwartz BD, Kannapell CC, Griffith RC, Scott MG, Ahmed P, Davie JM, Nahm MH, A unique DR-related B cell differentiation antigen. J Immunol131:2458-67 1983 |
| PubMed ID: 6415171 |
| |
| Daddona PE, Human adenosine deaminase. Properties and turnover in cultured T and B lymphoblasts. J Biol Chem256:12496-501 1981 |
| PubMed ID: 6975278 |
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| Carrel S, Gross N, Salvi S, Rabbit antiserum against Daudi-cell membrane fractions detects cell surface antigens present on subpopulations of human lymphocytes. J Immunol120:1587-93 1978 |
| PubMed ID: 307019 |
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| Lazarus H, Barell EF, Oppenheim S, Krishan A, Divergent properties of two human lymphocytic cell lines isolated from a single specimen of peripheral blood. In Vitro9:303-10 1974 |
| PubMed ID: 4523807 |
| |
| Adams RA, Flowers A, Davis BJ, Direct implantation and serial transplantation of human acute lymphoblastic leukemia in hamsters, SB-2. Cancer Res28:1121-5 1968 |
| PubMed ID: 4872716 |
| Split Ratio |
1:4 |
| Temperature |
37 C |
| Percent CO2 |
5% |
| Medium |
Roswell Park Memorial Institute Medium 1640 with 2mM L-glutamine or equivalent |
| Serum |
20% fetal bovine serum Not inactivated |
| Substrate |
None specified |
| Subcultivation Method |
dilution - add fresh medium |
| Supplement |
- |
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