GM08681
LCL from B-Lymphocyte
Description:
ANEUPLOID CHROMOSOME NUMBER - NON-TRISOMIC
|
Repository
|
NIGMS Human Genetic Cell Repository
|
| Subcollection |
Chromosome Abnormalities |
|
Biopsy Source
|
Peripheral vein
|
|
Cell Type
|
B-Lymphocyte
|
|
Tissue Type
|
Blood
|
|
Transformant
|
Epstein-Barr Virus
|
|
Sample Source
|
LCL from B-Lymphocyte
|
|
Race
|
White
|
|
Relation to Proband
|
proband
|
|
Confirmation
|
Karyotypic analysis after cell line submission to CCR
|
|
ISCN
|
47,XY,+i(18)(pter>p10:p10>pter)
|
|
Species
|
Homo sapiens
|
|
Common Name
|
Human
|
|
Remarks
|
|
| IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin Confirmed by Chromosome Analysis |
| |
| Cytogenetics |
Chromosome 18: ANEUPLOID Aneuploid Segment (+)18pter>18p10 |
|
Chromosome 18: ISOCHROMOSOME Aneuploid Segment (+)18pter>18p10 |
|
Chromosome 18: MARKER CHROMOSOME Aneuploid Segment (+)18pter>18p10 |
| Remarks |
Developmental delay, tracheomalacia, minor anomalies including scaphocephaly, narrow bifrontal diameter with decreased lateral scalp hair frontally, posteriorly rotated auricles, variant palmar crease patterns on hands, & hypertonia |
| Split Ratio |
1:5 |
| Temperature |
37 C |
| Percent CO2 |
5% |
| Medium |
Roswell Park Memorial Institute Medium 1640 with 2mM L-glutamine or equivalent |
| Serum |
15% fetal bovine serum Not Inactivated |
| Substrate |
None specified |
| Subcultivation Method |
dilution - add fresh medium |
| Supplement |
- |
|
|