| Demographic Data |
| Relation to Proband |
proband |
| Age at Sampling |
69 YR |
| Gender |
Male |
| Age of Onset(If not a control) |
67 YR |
| Age at Diagnosis(If not a control) |
No Data |
| Hispanic or Latino/Not Hispanic or Latino |
Not Hispanic/Latino |
| Racial Category |
Black/African American |
| Country |
USA |
| Diagnosed By |
No Data |
| |
| Data Elements |
| Clinical Element Type: Parkinsonism |
| (Baseline) |
| Longitudinal Data |
| Is this data Longitudinal (Follow-Up) Data? |
yes no |
| Family History |
| Family history of parkinsonism |
present absent unknown (subject adopted) |
| Specific diagnosis |
| Parkinsonism clinical diagnosis |
Parkinson's disease
Progressive Supranuclear Palsy
Diffuse Lewy Body Disease
Multiple System Atrophy
Others
Unaffected primary blood relative of proband
|
| Genetic Data of Subject |
| Mutation/s in subject's DNA (if present, describe) |
present absent unknown |
| Signs suggestive of PD diagnosis |
| Asymmetric onset |
present absent |
| Bradykinesis |
present absent |
| Activation tremor |
No Data |
| Resting Tremor |
present absent |
| Postural Instability |
present absent |
| Rigidity |
present absent |
| Gait difficulties |
present absent |
| Response to Anti-Parkinsonism Therapy |
tried and responsive inadequate dose not tried/not given tested and unresponsive |
| Signs suggestive of another diagnosis |
| history of strokes or stepwise deterioration |
present absent |
| history of head injury with loss of consciousness |
present absent |
| history of encephalitis |
present absent |
| Oculogyric crisis |
present absent |
| neuroleptic treatment at time of symptom onset |
present absent |
| sustained remission |
present absent |
| gaze palsy |
present absent |
| Cerebellar signs (other than activation tremor) |
present absent |
| Fluctuations |
No Data |
| hallucinations |
No Data |
| dysautonomia |
No Data |
| Memory loss |
No Data |
| axial rigidity |
No Data |
| Other |
present absent |
| Smoking History |
| smoking history |
No Data |
| years smoking |
No Data |
| Optional data |
| Mini-mental status score |
No Data |
| Hoehn and Yahr |
No Data |
| UPDRS total motor score |
No Data
Notes: 41.5 |
| Handedness |
No Data |
| Clinical Element Type: Parkinsonism |
| (Longitudinal, Series #2) |
| Longitudinal Data |
| Is this data Longitudinal (Follow-Up) Data? |
yes no |
| Family History |
| Family history of parkinsonism |
present absent unknown (subject adopted) |
| Specific diagnosis |
| Parkinsonism clinical diagnosis |
Parkinson's disease
Progressive Supranuclear Palsy
Diffuse Lewy Body Disease
Multiple System Atrophy
Others
Unaffected primary blood relative of proband
|
| Genetic Data of Subject |
| Mutation/s in subject's DNA (if present, describe) |
present absent unknown |
| Signs suggestive of PD diagnosis |
| Asymmetric onset |
present absent |
| Bradykinesis |
present absent |
| Activation tremor |
present absent |
| Resting Tremor |
present absent |
| Postural Instability |
present absent |
| Rigidity |
present absent |
| Gait difficulties |
present absent |
| Response to Anti-Parkinsonism Therapy |
tried and responsive inadequate dose not tried/not given tested and unresponsive |
| Signs suggestive of another diagnosis |
| history of strokes or stepwise deterioration |
present absent |
| history of head injury with loss of consciousness |
present absent |
| history of encephalitis |
present absent |
| Oculogyric crisis |
present absent |
| neuroleptic treatment at time of symptom onset |
present absent |
| sustained remission |
present absent |
| gaze palsy |
present absent |
| Cerebellar signs (other than activation tremor) |
present absent |
| Fluctuations |
present absent |
| hallucinations |
present absent |
| dysautonomia |
present absent |
| Memory loss |
present absent |
| axial rigidity |
present absent |
| Other |
present absent |
| Smoking History |
| smoking history |
never former smoker current smoker |
| years smoking |
No Data |
| Optional data |
| Mini-mental status score |
22 |
| Hoehn and Yahr |
No Data |
| UPDRS total motor score |
No Data |
| Handedness |
Right Left Ambidextrous |
| Clinical Element Type: Parkinsonism |
| (Longitudinal, Series #3) |
| Longitudinal Data |
| Is this data Longitudinal (Follow-Up) Data? |
yes no |
| Family History |
| Family history of parkinsonism |
present absent unknown (subject adopted) |
| Specific diagnosis |
| Parkinsonism clinical diagnosis |
Parkinson's disease
Progressive Supranuclear Palsy
Diffuse Lewy Body Disease
Multiple System Atrophy
Others
Unaffected primary blood relative of proband
|
| Genetic Data of Subject |
| Mutation/s in subject's DNA (if present, describe) |
present absent unknown |
| Signs suggestive of PD diagnosis |
| Asymmetric onset |
present absent |
| Bradykinesis |
present absent |
| Activation tremor |
present absent |
| Resting Tremor |
present absent |
| Postural Instability |
present absent |
| Rigidity |
present absent |
| Gait difficulties |
present absent |
| Response to Anti-Parkinsonism Therapy |
tried and responsive inadequate dose not tried/not given tested and unresponsive |
| Signs suggestive of another diagnosis |
| history of strokes or stepwise deterioration |
present absent |
| history of head injury with loss of consciousness |
present absent |
| history of encephalitis |
present absent |
| Oculogyric crisis |
present absent |
| neuroleptic treatment at time of symptom onset |
present absent |
| sustained remission |
present absent |
| gaze palsy |
present absent |
| Cerebellar signs (other than activation tremor) |
present absent |
| Fluctuations |
present absent |
| hallucinations |
present absent |
| dysautonomia |
present absent |
| Memory loss |
present absent |
| axial rigidity |
present absent |
| Other |
present absent |
| Smoking History |
| smoking history |
never former smoker current smoker |
| years smoking |
No Data |
| Optional data |
| Mini-mental status score |
22 |
| Hoehn and Yahr |
No Data |
| UPDRS total motor score |
No Data |
| Handedness |
Right Left Ambidextrous |
| Clinical Element Type: Parkinsonism |
| (Longitudinal, Series #4) |
| Longitudinal Data |
| Is this data Longitudinal (Follow-Up) Data? |
yes no |
| Family History |
| Family history of parkinsonism |
present absent unknown (subject adopted) |
| Specific diagnosis |
| Parkinsonism clinical diagnosis |
Parkinson's disease
Progressive Supranuclear Palsy
Diffuse Lewy Body Disease
Multiple System Atrophy
Others
Unaffected primary blood relative of proband
|
| Genetic Data of Subject |
| Mutation/s in subject's DNA (if present, describe) |
present absent unknown |
| Signs suggestive of PD diagnosis |
| Asymmetric onset |
present absent |
| Bradykinesis |
present absent |
| Activation tremor |
present absent |
| Resting Tremor |
present absent |
| Postural Instability |
present absent |
| Rigidity |
present absent |
| Gait difficulties |
present absent |
| Response to Anti-Parkinsonism Therapy |
tried and responsive inadequate dose not tried/not given tested and unresponsive |
| Signs suggestive of another diagnosis |
| history of strokes or stepwise deterioration |
present absent |
| history of head injury with loss of consciousness |
present absent |
| history of encephalitis |
present absent |
| Oculogyric crisis |
present absent |
| neuroleptic treatment at time of symptom onset |
present absent |
| sustained remission |
present absent |
| gaze palsy |
present absent |
| Cerebellar signs (other than activation tremor) |
present absent |
| Fluctuations |
present absent |
| hallucinations |
present absent |
| dysautonomia |
present absent |
| Memory loss |
present absent |
| axial rigidity |
present absent |
| Other |
present absent |
| Smoking History |
| smoking history |
never former smoker current smoker |
| years smoking |
No Data |
| Optional data |
| Mini-mental status score |
No Data |
| Hoehn and Yahr |
No Data |
| UPDRS total motor score |
No Data |
| Handedness |
Right Left Ambidextrous |
| Clinical Element Type: Parkinsonism |
| (Longitudinal, Series #5) |
| Longitudinal Data |
| Is this data Longitudinal (Follow-Up) Data? |
yes no |
| Family History |
| Family history of parkinsonism |
present absent unknown (subject adopted) |
| Specific diagnosis |
| Parkinsonism clinical diagnosis |
Parkinson's disease
Progressive Supranuclear Palsy
Diffuse Lewy Body Disease
Multiple System Atrophy
Others
Unaffected primary blood relative of proband
|
| Genetic Data of Subject |
| Mutation/s in subject's DNA (if present, describe) |
present absent unknown |
| Signs suggestive of PD diagnosis |
| Asymmetric onset |
present absent |
| Bradykinesis |
present absent |
| Activation tremor |
present absent |
| Resting Tremor |
present absent |
| Postural Instability |
present absent |
| Rigidity |
present absent |
| Gait difficulties |
present absent |
| Response to Anti-Parkinsonism Therapy |
tried and responsive inadequate dose not tried/not given tested and unresponsive |
| Signs suggestive of another diagnosis |
| history of strokes or stepwise deterioration |
present absent |
| history of head injury with loss of consciousness |
present absent |
| history of encephalitis |
present absent |
| Oculogyric crisis |
present absent |
| neuroleptic treatment at time of symptom onset |
present absent |
| sustained remission |
present absent |
| gaze palsy |
present absent |
| Cerebellar signs (other than activation tremor) |
present absent |
| Fluctuations |
present absent |
| hallucinations |
present absent |
| dysautonomia |
present absent |
| Memory loss |
present absent |
| axial rigidity |
present absent |
| Other |
present absent |
| Smoking History |
| smoking history |
never former smoker current smoker |
| years smoking |
No Data |
| Optional data |
| Mini-mental status score |
No Data |
| Hoehn and Yahr |
No Data |
| UPDRS total motor score |
No Data |
| Handedness |
Right Left Ambidextrous |
| Clinical Element Type: Parkinsonism |
| (Longitudinal, Series #6) |
| Longitudinal Data |
| Is this data Longitudinal (Follow-Up) Data? |
yes no |
| Family History |
| Family history of parkinsonism |
present absent unknown (subject adopted) |
| Specific diagnosis |
| Parkinsonism clinical diagnosis |
Parkinson's disease
Progressive Supranuclear Palsy
Diffuse Lewy Body Disease
Multiple System Atrophy
Others
Unaffected primary blood relative of proband
|
| Genetic Data of Subject |
| Mutation/s in subject's DNA (if present, describe) |
present absent unknown |
| Signs suggestive of PD diagnosis |
| Asymmetric onset |
present absent |
| Bradykinesis |
present absent |
| Activation tremor |
present absent |
| Resting Tremor |
present absent |
| Postural Instability |
present absent |
| Rigidity |
present absent |
| Gait difficulties |
present absent |
| Response to Anti-Parkinsonism Therapy |
tried and responsive inadequate dose not tried/not given tested and unresponsive |
| Signs suggestive of another diagnosis |
| history of strokes or stepwise deterioration |
present absent |
| history of head injury with loss of consciousness |
present absent |
| history of encephalitis |
present absent |
| Oculogyric crisis |
present absent |
| neuroleptic treatment at time of symptom onset |
present absent |
| sustained remission |
present absent |
| gaze palsy |
present absent |
| Cerebellar signs (other than activation tremor) |
present absent |
| Fluctuations |
present absent |
| hallucinations |
present absent |
| dysautonomia |
present absent |
| Memory loss |
present absent |
| axial rigidity |
present absent |
| Other |
present absent |
| Smoking History |
| smoking history |
never former smoker current smoker |
| years smoking |
No Data |
| Optional data |
| Mini-mental status score |
No Data |
| Hoehn and Yahr |
No Data |
| UPDRS total motor score |
No Data |
| Handedness |
Right Left Ambidextrous |