NA00005
DNA from Fibroblast
Description:
TRANSLOCATED CHROMOSOME
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Repository
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NIGMS Human Genetic Cell Repository
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| Subcollection |
Chromosome Abnormalities |
| Quantity |
10 µg |
| Quantitation Method |
Please see our FAQ |
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Biopsy Source
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Arm
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Cell Type
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Fibroblast
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Tissue Type
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Skin
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Transformant
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Untransformed
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Sample Source
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DNA from Fibroblast
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Race
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White
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Relation to Proband
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proband
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Confirmation
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Karyotypic analysis after cell line submission to CCR
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ISCN
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45,XX,der(14;22)(14qter>14q10::22q10>22qter)
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Species
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Homo sapiens
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Common Name
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Human
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Remarks
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| Passage Frozen |
5 |
| |
| IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin Confirmed by Chromosome Analysis |
| |
| Cytogenetics |
Chromosome 14: TRANSLOCATION Breakpoint 14cen t(14;22)14cen |
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Chromosome 22: TRANSLOCATION Breakpoint 22cen t(14;22)22cen |
| Remarks |
Clinically normal |
| Page SL, Shin JC, Han JY, Choo KH, Shaffer LG, Breakpoint diversity illustrates distinct mechanisms for Robertsonian translocation formation. Hum Mol Genet5(9):1279-88 1996 |
| PubMed ID: 8872467 |
| |
| Sundar Raj CV, Church RL, Klobutcher LA, Ruddle FH, Genetics of the connective tissue proteins: assignment of the gene for human type I procollagen to chromosome 17 by analysis of cell hybrids and microcell hybrids. Proc Natl Acad Sci U S A74:4444-8 1977 |
| PubMed ID: 412188 |
| |
| Faber HE, Kucherlapati RS, Poulik MD, Ruddle FH, Smithies O, beta2-microglobulin locus on human chromosome 15. Somatic Cell Genet2:141-53 1976 |
| PubMed ID: 69326 |
| |
| Faber HE, Kucherlapati RS, Poulik MD, Ruddle FH, Smithies O, A (14;22) Robertsonian translocation, 45 chromosomes. Human Genetic Mutant Cell Repository, Camden, N.J., identification No. GM-5. Cytogenet Cell Genet12:368-9 1973 |
| PubMed ID: 4780772 |
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