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NA01056 DNA from LCL

Description:

APPARENTLY HEALTHY INDIVIDUAL

Affected:

No

Sex:

Male

Age:

65 YR (At Sampling)

  • Overview
  • Characterizations
  • Phenotypic Data
  • Publications
  • External Links

Overview

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Repository NIGMS Human Genetic Cell Repository
Subcollection Apparently Healthy Collection
Alternate IDs GM17211 [APPARENTLY HEALTHY INDIVIDUAL]
Quantity 25 µg
Quantitation Method Please see our FAQ
Biopsy Source Peripheral vein
Cell Type B-Lymphocyte
Tissue Type Blood
Transformant Epstein-Barr Virus
Sample Source DNA from LCL
Race White
Family Member 1
Relation to Proband proband
Confirmation Karyotypic analysis and Case history
Species Homo sapiens
Common Name Human
Remarks HLA type A9,29,B12,Bw15; secretes IgA2 (Lambda); 46,XY; 8% of cells show random chromosome loss/gain; see GM09918 Fibro

Characterizations

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IDENTIFICATION OF SPECIES OF ORIGIN Species of Origin Confirmed by Nucleoside Phosphorylase, Glucose-6-Phosphate Dehydrogenase, and Lactate Dehydrogenase Isoenzyme Electrophoresis and by Chromosome Analysis
 
IMMUNOGLOBULIN PRODUCTION Lymphoid Culture Secretes IgA2 (Lambda)
 

Phenotypic Data

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Remarks HLA type A9,29,B12,Bw15; secretes IgA2 (Lambda); 46,XY; 8% of cells show random chromosome loss/gain; see GM09918 Fibro

Publications

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Sotamaa K, Liyanarachchi S, Mecklin JP, Järvinen H, Aaltonen LA, Peltomäki P, de la Chapelle A, p53 codon 72 and MDM2 SNP309 polymorphisms and age of colorectal cancer onset in Lynch syndrome Clinical cancer research : an official journal of the American Association for Cancer Research11:6840-4 2005
PubMed ID: 16203772
 
Pastinen T, Sladek R, Gurd S, Sammak A, Ge B, Lepage P, Lavergne K, Villeneuve A, Gaudin T, Brandstrom H, Beck A, Verner A, Kingsley J, Harmsen E, Labuda D, Morgan K, Vohl MC, Naumova AK, Sinnett D, Hudson TJ, A survey of genetic and epigenetic variation affecting human gene expression. Physiol Genomics16(2):184-93 2004
PubMed ID: 14583597
 
Diaz-Sanchez D, Dotson AR, Takenaka H, Saxon A, Diesel exhaust particles induce local IgE production in vivo and alter the pattern of IgE messenger RNA isoforms. J Clin Invest94:1417-25 1994
PubMed ID: 7523450
 
Reardon JT, Thompson LH, Sancar A, Excision repair in man and the molecular basis of xeroderma pigmentosum syndrome. Cold Spring Harb Symp Quant Biol58:605-17 1993
PubMed ID: 7956075
 
Takai S, Price FM, Sanford KK, Tarone RE, Parshad R, Persistence of chromatid damage after G2 phase X-irradiation in lymphoblastoid cells from Gardner's syndrome. Carcinogenesis11:1425-8 1990
PubMed ID: 2387030
 
Moore JS, Prystowsky MB, Hoover RG, Besa EC, Nowell PC, Defective T cell-mediated, isotype-specific immunoglobulin regulation in B cell chronic lymphocytic leukemia. Blood71:1012-20 1988
PubMed ID: 2895674
 
Yemul S, Berger C, Estabrook A, Suarez S, Edelson R, Bayley H, Selective killing of T lymphocytes by phototoxic liposomes. Proc Natl Acad Sci U S A84:246-50 1987
PubMed ID: 3491992
 
Haluska FG, Finver S, Tsujimoto Y, Croce CM, The t(8; 14) chromosomal translocation occurring in B-cell malignancies results from mistakes in V-D-J joining. Nature324:158-61 1986
PubMed ID: 3097550
 
Mixter PF, Wu SV, Studnicka GM, Robinson RR, A simple, computer-assisted assay to detect isotype-specific regulation of human immunoglobulin synthesis. J Immunol Methods91:195-203 1986
PubMed ID: 3755453
 
Sun LK, Showe LC, Croce CM, Analysis of the 3' flanking region of the human c-myc gene in lymphomas with the t(8;22) and t(2;8) chromosomal translocations. Nucleic Acids Res14:4037-50 1986
PubMed ID: 3714470
 
Isobe M, Erikson J, Emanuel BS, Nowell PC, Croce CM, Location of gene for beta subunit of human T-cell receptor at band 7q35, a region prone to rearrangements in T cells. Science228:580-2 1985
PubMed ID: 3983641
 
Max EE, Korsmeyer SJ, Human J chain gene. Structure and expression in B lymphoid cells. J Exp Med161:832-49 1985
PubMed ID: 2984306
 
Nishikura K, ar-Rushdi A, Erikson J, Watt R, Rovera G, Croce CM, Differential expression of the normal and of the translocated human c- myc oncogenes in B cells. Proc Natl Acad Sci U S A80:4822-6 1983
PubMed ID: 6308654
 
Erikson J, Martinis J, Croce CM, Assignment of the genes for human lambda immunoglobulin chains to chromosome 22. Nature294:173-175 1981
PubMed ID: 6795508
 
Dolby TW, Devuono J, Croce CM, Cloning and partial nucleotide sequence of human immunoglobulin mu chain cDNA from B cells and mouse-human hybridomas. Proc Natl Acad Sci U S A77:6027-31 1980
PubMed ID: 6777778
 
McGarrity GJ, Phillips DM, Vaidya AB, Mycoplasmal infection of lymphocyte cell cultures: infection with M. salivarium. In Vitro16:346-56 1980
PubMed ID: 7399547
 
Croce CM, Shander M, Martinis J, Cicurel L, D'Ancona GG, Dolby TW, Koprowski H, Chromosomal location of the genes for human immunoglobulin heavy chains. Proc Natl Acad Sci U S A76:3416-9 1979
PubMed ID: 114999
 
Moses RE, Beaudet AL, Apurinic DNA endonuclease activities in repair-deficient human cell lines. Nucleic Acids Res5:463-73 1978
PubMed ID: 634794

External Links

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dbSNP dbSNP ID: 10382
Pricing
International/Commercial/For-profit:
$281.00USD
U.S. Academic/Non-profit/Government:
$139.00USD
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How to Order
  • Ordering Instructions
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