NA01605
DNA from Fibroblast
Description:
TRANSLOCATED CHROMOSOME
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Repository
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NIGMS Human Genetic Cell Repository
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| Subcollection |
Chromosome Abnormalities |
| Quantity |
50 µg |
| Quantitation Method |
Please see our FAQ |
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Cell Type
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Fibroblast
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Transformant
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Untransformed
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Sample Source
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DNA from Fibroblast
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Race
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White
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Relation to Proband
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proband
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Confirmation
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Karyotypic analysis after cell line submission to CCR
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ISCN
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46,XY,t(6;11)(6qter>6p23::11q23>11qter; 11pter>11q23::6p23>6pter)
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Species
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Homo sapiens
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Common Name
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Human
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Remarks
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| Passage Frozen |
3 |
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| IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin Confirmed by Chromosome Analysis |
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| Cytogenetics |
Chromosome 11: TRANSLOCATION Breakpoint 11q23 t(6;11)11q23 |
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Chromosome 6: TRANSLOCATION Breakpoint 6p23 t(6;11)6p23 |
| Remarks |
Phenotypically normal with a family history of infertility and spontaneous abortions |
| Rovigatti U, Watson DK, Yunis JJ, Amplification and rearrangement of Hu-ets-1 in leukemia and lymphoma with involvement of 11q23. Science232:398-400 1986 |
| PubMed ID: 3457468 |
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| Wright YM, Clark WE, Breg WR, Craniorachischisis in a partially trisomic 11 fetus in a family with reproductive failure and a reciprocal translocation, t(6p plus;11q minus). J Med Genet11:69-75 1974 |
| PubMed ID: 4134620 |
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