ED149357

ED149357 DNA

Description:

AGE-RELATED MACULAR DEGENERATION; AMD
AREDS2 DNA FROM WB dbGaP ID AR2_0015

Affected:

Yes

Sex:

Female

Age:

73 YR (At Sampling)

Overview

Repository

AREDS2

Quantity

1 µg

Quantitation Method

Please see our FAQ

Race

White

Ethnicity

Not Hispanic/Latino

Relation to Proband

proband

Species

Homo sapiens

Common Name

Human

Remarks

1 µg DNA, not extracted at Coriell, reported Qubit conc=100.4 µg/mL, reported A260/A280=2.0

Phenotypic Data

AREDS2 Clinical Data
These data are not intended for analysis and should be used only for sample selection purposes. For analyses, the actual Central GA, any GA and NV AMD fields from the fundus grading datasets (AREDS2_RCA and AREDS2_RCF) are available in the AREDS2 dbGaP.

dbGaP Submitter Subject Id

AR2_0015

Consent Status

GRU - General Research Use

Control

Age (Yrs)

Gender

Female

Race

White

Ethnicity

Not Hispanic or Latino

RE Baseline AMD Severity Scale

6 - AREDS AMD Severity Scale Step 6

RE Final AMD Severity Scale

7 - AREDS AMD Severity Scale Step 7

RE Final Graded Visit

Year 5

LE Baseline AMD Severity Scale

7 - AREDS AMD Severity Scale Step 7

LE Final AMD Severity Scale

11b - Neovascular AMD with end-stage disease (e.g., definite disciform scar, or photocoagulation scar), or two or more of the following five characteristics of neovascular AMD: SSR detachment, PED, subretinal/sub-RPE hemorrhage, hard exudate, or fibrous tissue

LE Final Graded Visit

Year 5

Data Definition References

Evaluating the Validity of the Age-Related Eye Disease Study Grading Scale for Age-Related Macular Degeneration: AREDS2 Report 10 (2016)
doi: 10.1001/jamaophthalmol.2016.2383; PMID: 27442263; PMCID: PMC8371745

The Age-Related Eye Disease Study severity scale for age-related macular degeneration: AREDS Report No. 17 (2005)
doi: 10.1001/archopht.123.11.1484; PMID: 16286610; PMCID: PMC1472813

Other Study References

Long-term Outcomes of Adding Lutein/Zeaxanthin and ω-3 Fatty Acids to the AREDS Supplements on Age-Related Macular Degeneration Progression AREDS2 Report 28 (2022)
doi: 10.1001/jamaophthalmol.2022.1640; PMID: 35653117; PMCID: PMC9164119

Age-Related Eye Disease Study 2 Report Number 12 by the Age-Related Eye Disease Study 2 Optos PEripheral RetinA (OPERA) Study Research Group (2016)
doi: 10.1016/j.ophtha.2016.12.004; PMID: 28089680

The Age-Related Eye Disease Study 2 (AREDS2): study design and baseline characteristics (AREDS2 report number 1) (2012)
doi: 10.1016/j.ophtha.2012.05.027; PMID: 22840421; PMCID: PMC3485447

External Links

dbGaP Link

phs002015.v1.p1

Culture Protocols

Supplement

Pricing

Commercial:

$200.00USD

Academic &
Non-profit:

$100.00USD

NEI-grantee

$75.00USD

Description:

AGE-RELATED MACULAR DEGENERATION; AMD AREDS2 DNA FROM WB dbGaP ID AR2_0015

Affected:

Yes

Sex:

Female

Age:

73 YR (At Sampling)

Overview

Phenotypic Data

External Links

Culture Protocols

AGE-RELATED MACULAR DEGENERATION; AMD
AREDS2 DNA FROM WB dbGaP ID AR2_0015