AG07961
Fibroblast from Skin, Arm
Description:
XERODERMA PIGMENTOSUM: COMPLEMENTATION GROUP UNDETERMINED
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Repository
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NIA Aging Cell Culture Repository
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| Subcollection |
Heritable Diseases |
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Biopsy Source
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Arm
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Cell Type
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Fibroblast
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Tissue Type
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Skin
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Transformant
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Untransformed
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Sample Source
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Fibroblast from Skin, Arm
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Race
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White
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Ethnicity
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FINNISH
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Family Member
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6
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Relation to Proband
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sister
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Confirmation
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Clinical summary/Case history
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Species
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Homo sapiens
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Common Name
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Human
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Remarks
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| Remarks |
The Finnish donor is a clinically unaffected sib of 3 affecteds. The skin biopsy was taken ante-mortem on 11/30/84 from the inner aspect of the upper left arm. The culture was initiated using explants of minced skin tissue. The cell morphology is fibroblast-like. A lymphoblast culture from same donor is AG07960. |
| Buchaklian AH, Helbling D, Ware SM, Dimmock DP, Recessive deoxyguanosine kinase deficiency causes juvenile onset mitochondrial myopathy Molecular genetics and metabolism: 2012 |
| PubMed ID: 22622127 |
| Cumulative PDL at Freeze |
5 |
| Split Ratio |
1:3 |
| Temperature |
37 C |
| Percent CO2 |
5% |
| Medium |
Eagle's Minimum Essential Medium with Earle's salts and non-essential amino acids with 2mM L-glutamine or equivalent |
| Serum |
15% fetal bovine serum Not inactivated |
| Substrate |
None specified |
| Subcultivation Method |
trypsin-EDTA |
| Supplement |
- |
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