NA00126
DNA from Fibroblast
Description:
TRANSLOCATED CHROMOSOME
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Repository
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NIGMS Human Genetic Cell Repository
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| Subcollection |
Chromosome Abnormalities |
| Quantity |
50 µg |
| Quantitation Method |
Please see our FAQ |
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Cell Type
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Fibroblast
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Transformant
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Untransformed
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Sample Source
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DNA from Fibroblast
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Race
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White
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Relation to Proband
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proband
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Confirmation
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Karyotypic analysis after cell line submission to CCR
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ISCN
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46,XY,t(1;15)(1qter>1p36.1::15q11.2> 15qter;15pter>15q11.2::1p36.1>1pter)
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Species
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Homo sapiens
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Common Name
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Human
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Remarks
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| Passage Frozen |
4 |
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| IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin Confirmed by Chromosome Analysis |
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| Cytogenetics |
Chromosome 1: TRANSLOCATION Breakpoint 1p36 t(1;15)1p36 |
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Chromosome 15: TRANSLOCATION Breakpoint 15q11 t(1;15)15q11 |
| Remarks |
Clinically normal |
| Barker PE, Rabin M, Watson M, Breg WR, Ruddle FH, Verma IM, Human c-fos oncogene mapped within chromosomal region 14q21----q31. Proc Natl Acad Sci U S A81:5826-30 1984 |
| PubMed ID: 6091112 |
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| Lidksy AS, Robson KJ, Thirumalachary C, Barker PE, Ruddle FH, Woo SL, The PKU locus in man is on chromosome 12. Am J Hum Genet36:527-33 1984 |
| PubMed ID: 6547271 |
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| Maurer BJ, Barker PE, Masters JN, Ruddle FH, Attardi G, Human dihydrofolate reductase gene is located in chromosome 5 and is unlinked to the related pseudogenes. Proc Natl Acad Sci U S A81:1484-8 1984 |
| PubMed ID: 6584893 |
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| Shulman LM, Barker PE, Hart JT, Messer Peters PG, Ruddle FH, Assignment of low-molecular-weight human (2', 5')A synthetase to chromosome 11. Somat Cell Mol Genet10:247-57 1984 |
| PubMed ID: 6585970 |
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| Kamarck ME, Barbosa JA, Ruddle FH, Somatic cell genetic analysis of HLA-A, B, C and human beta 2- microglobulin expression. Somatic Cell Genet8:385-402 1982 |
| PubMed ID: 6180489 |
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| Peters PG, Kamarck ME, Hemler ME, Strominger JL, Ruddle FH, Genetic and biochemical characterization of a human surface determinant on somatic cell hybrids: the 4F2 antigen. Somatic Cell Genet8:825-34 1982 |
| PubMed ID: 6187076 |
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| Mellman IS, Lin PF, Ruddle FH, Rosenberg LE, Genetic control of cobalamin binding in normal and mutant cells: assignment of the gene for 5-methyltetrahydrofolate:L-homocysteine S- methyltransferase to human chromosome 1. Proc Natl Acad Sci U S A76:405-9 1979 |
| PubMed ID: 284356 |
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| Deisseroth A, Nienhuis A, Lawrence J, Giles R, Turner P, Ruddle FH, Chromosomal localization of human beta globin gene on human chromosome 11 in somatic cell hybrids. Proc Natl Acad Sci U S A75:1456-60 1978 |
| PubMed ID: 274732 |
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| Prescott GH, McCaw BK, Tolby BE, Hecht F, Miller RC, Greene AE, Coriell LL, A (1;15) translocation, balanced, 46 chromosomes. Repository identification No. GM-126. Cytogenet Cell Genet14:84-6 1975 |
| PubMed ID: 1132252 |
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