NG04662
DNA from Fibroblast
Description:
GERONTOLOGY RESEARCH CENTER (GRC) CELL CULTURE COLLECTION
BALTIMORE LONGITUDINAL STUDY ON AGING (BLSA)
Repository
|
NIA Aging Cell Culture Repository
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Subcollection |
GRC |
Quantity |
10 µg |
Quantitation Method |
Please see our FAQ |
Biopsy Source
|
Arm
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Cell Type
|
Fibroblast
|
Tissue Type
|
Skin
|
Transformant
|
Untransformed
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Sample Source
|
DNA from Fibroblast
|
Race
|
White
|
Family Member
|
2
|
Relation to Proband
|
father
|
Confirmation
|
Clinical summary/Case history
|
ISCN
|
45,X[22]/47,XY,+7[7]/46,XY[21]
|
Species
|
Homo sapiens
|
Common Name
|
Human
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Remarks
|
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PDL at Freeze |
13 |
|
IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin Confirmed by Nucleoside Phosphorylase, Glucose-6-Phosphate Dehydrogenase, and Lactate Dehydrogenase Isoenzyme Electrophoresis and by Chromosome Analysis |
|
Remarks |
The biopsy site is the mesial aspect of the mid-upper left arm, taken antemortem. The primary culture was initiated from explants of a 2 mm-punch biopsy. The cell morphology is fibroblast-like. The culture is a mosaic with karyotype: 46,XY/45,X; 54%/46%. Donor's son is AG13095. The legacy karyotype description shown in this Remark may not be representative of the current available product. |
Fleischer JG, Schulte R, Tsai HH, Tyagi S, Ibarra A, Shokhirev MN, Huang L, Hetzer MW, Navlakha S, Predicting age from the transcriptome of human dermal fibroblasts Genome Biology19: 2018 |
PubMed ID: 30567591 |
|
Schneider EL, Monticone R, Smith J, Braunschweiger K, Roberts T, Skin fibroblast cultures derived from members of the Baltimore longitudinal study: a new resource for studies of cellular aging. Cytogenet Cell Genet31:40-6 1981 |
PubMed ID: 7307581 |
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