Description:
SARDINIAN POPULATION OF GREAT AGE
APPARENTLY HEALTHY INDIVIDUAL
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Repository
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NIA Aging Cell Culture Repository
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| Subcollection |
Apparently Healthy Collection |
| Quantity |
10ug |
| Quantitation Method |
Please see our FAQ |
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Biopsy Source
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Peripheral vein
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Cell Type
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B-Lymphocyte
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Tissue Type
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Blood
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Transformant
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Epstein-Barr Virus
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Sample Source
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DNA from LCL
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Race
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White
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Ethnicity
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ITALIAN
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Relation to Proband
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proband
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Confirmation
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Clinical summary/Case history
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ISCN
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45,XY,der(14;21)(q10;q10)
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Species
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Homo sapiens
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Common Name
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Human
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Remarks
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| IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin Confirmed by Nucleoside Phosphorylase, Glucose-6-Phosphate Dehydrogenase, and Lactate Dehydrogenase Isoenzyme Electrophoresis and by Chromosome Analysis |
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| Remarks |
Healthy nonagenarian from Carloforte, a city on San Pietro, an island off the southwest coast of Sardinia, and from a population very largely originating in Genoa in the 18th century. This individual was not related to the other members of the Carloforte collection for two generations and lived to be 96 years of age.The culture was initiated on 7/7/97 by transformation of lymphocytes with Epstein Barr virus. The culture grows in suspension and the cell morphology is spherical. The karyotype is 45,XY,der(14;21)(q10;q10) with 2% of the cells examined showing random chromosomal aberrations. The legacy karyotype description shown in this Remark may not be representative of the current available product. |
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