Description:
APPARENTLY HEALTHY INDIVIDUAL
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Repository
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NIA Aging Cell Culture Repository
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| Subcollection |
"Intra-abdominal fat and risk of disease in children and adolescents" study
Apparently Healthy Collection |
| Quantity |
10 µg |
| Quantitation Method |
Please see our FAQ |
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Biopsy Source
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Peripheral vein
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Cell Type
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B-Lymphocyte
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Tissue Type
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Blood
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Transformant
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Epstein-Barr Virus
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Sample Source
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DNA from LCL
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Race
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White
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Relation to Proband
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proband
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Confirmation
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Clinical summary/Case history
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ISCN
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46,XY
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Species
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Homo sapiens
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Common Name
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Human
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Remarks
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| IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin Confirmed by Nucleoside Phosphorylase, Glucose-6-Phosphate Dehydrogenase, and Lactate Dehydrogenase Isoenzyme Electrophoresis |
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| Remarks |
Participant in the "intra-abdominal fat and risk of disease in children and adolescents" study. The culture was initiated on 2/10/98 by transformation of lymphocytes with Epstein Barr virus. The culture grows in suspension and the cell morphology is spherical. The karyotype is 46,XY with 2% of the cells examined showing random chromosome loss. The legacy karyotype description shown in this Remark may not be representative of the current available product. |
| San Roman AK, Godfrey AK, Skaletsky H, Bellott DW, Groff AF, Harris HL, Blanton LV, Hughes JF, Brown L, Phou S, Buscetta A, Kruszka P, Banks N, Dutra A, Pak E, Lasutschinkow PC, Keen C, Davis SM, Tartaglia NR, Samango-Sprouse C, Muenke M, Page DC, The human inactive X chromosome modulates expression of the active X chromosome Cell genomics3:100259 2022 |
| PubMed ID: 36819663 |
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| Suganuma T, Workman JL, MPTAC links alkylation damage signaling to sterol biosynthesis Redox biology51:102270 2021 |
| PubMed ID: 35189552 |
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| Zhong XZ1, Zou Y1, Sun X1,2, Dong G1, Cao Q1, Pandey A3, Rainey JK3,4, Zhu X2, Dong XP5., Inhibition of Transient Receptor Potential Channel Mucolipin-1 (TRPML1) by Lysosomal Adenosine Involved in Severe Combined Immunodeficiency Diseases. J Biol Chem.292(8):3445-3455 2017 |
| PubMed ID: 28087698 |
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| Tsumagari K, Qi L, Jackson K, Shao C, Lacey M, Sowden J, Tawil R, Vedanarayanan V, Ehrlich M, Epigenetics of a tandem DNA repeat: chromatin DNaseI sensitivity and opposite methylation changes in cancers Nucleic acids research36:2196-207 2008 |
| PubMed ID: 18281700 |
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| Nishiyama R, Qi L, Lacey M, Ehrlich M, Both hypomethylation and hypermethylation in a 0.2-kb region of a DNA repeat in cancer. Mol Cancer Res3(11):617-26 2005 |
| PubMed ID: 16317087 |
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| Gisselsson D, Shao C, Tuck-Muller CM, Sogorovic S, Pålsson E, Smeets D, Ehrlich M, Interphase chromosomal abnormalities and mitotic missegregation of hypomethylated sequences in ICF syndrome cells Chromosoma114:118-26 2004 |
| PubMed ID: 15856360 |
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| Goran MI, Metabolic precursors and effects of obesity in children: a decade of progress, 1990-1999. Am J Clin Nutr73(2):158-71 2001 |
| PubMed ID: 11157310 |
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| Goran MI, Bergman RN, Gower BA, Influence of total vs. visceral fat on insulin action and secretion in African American and white children. Obes Res9(8):423-31 2001 |
| PubMed ID: 11500522 |
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| Goran MI, Gower BA, Longitudinal study on pubertal insulin resistance. Diabetes50(11):2444-50 2001 |
| PubMed ID: 11679420 |
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| Herd SL, Gower BA, Dashti N, Goran MI, Body fat, fat distribution and serum lipids, lipoproteins and apolipoproteins in African-American and Caucasian-American prepubertal children. Int J Obes Relat Metab Disord25(2):198-204 2001 |
| PubMed ID: 11410820 |
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| Huang TT, Johnson MS, Figueroa-Colon R, Dwyer JH, Goran MI, Growth of visceral fat, subcutaneous abdominal fat, and total body fat in children. Obes Res9(5):283-9 2001 |
| PubMed ID: 11346669 |
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| Johnson MS, Figueroa-Colon R, Huang TT, Dwyer JH, Goran MI, Longitudinal changes in body fat in African American and Caucasian children: influence of fasting insulin and insulin sensitivity. J Clin Endocrinol Metab86(7):3182-7 2001 |
| PubMed ID: 11443186 |
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| Li C, Johnson MS, Goran MI, Effects of low birth weight on insulin resistance syndrome in caucasian and African-American children. Diabetes Care24(12):2035-42 2001 |
| PubMed ID: 11723079 |
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| Sun M, Gower BA, Bartolucci AA, Hunter GR, Figueroa-Colon R, Goran MI, A longitudinal study of resting energy expenditure relative to body composition during puberty in African American and white children. Am J Clin Nutr73(2):308-15 2001 |
| PubMed ID: 11157329 |
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| Goran MI, Visceral fat in prepubertal children: Influence of obesity, anthropometry, ethnicity, gender, diet, and growth. Am J Human Biol11(2):201-207 1999 |
| PubMed ID: 11533944 |
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