Colombian in Medellín, Colombia [CLM]

Available Samples Family Relationships
Cell Cultures: 136
   
DNA: 136
   
DNA Sample Panel: MGP00005
   
 
 Trios:  36
   
 Unrelated Individuals:  28
   

 
   
 

Population Description

These cell lines and DNA samples were prepared from blood samples collected in the Medellín, Colombia, metropolitan area. All parents in the trios identified themselves as having all four grandparents born in Colombia. Although individuals from the Medellín metropolitan area can originate in different parts of Colombia, this set of samples should not be seen as representative of the entire population of Colombia, which is regionally highly diverse. Note that the correct spelling is: Colombian and not Columbian, and also that Medellín has an accent on the (i).

Referring to Populations

These samples should not be referred to as “Hispanic” or “Latino” since these are cultural designators, encompassing populations with very diverse ancestries.

The full population descriptor is Colombian in Medellín, Colombia. The shorthand label is Colombian and the abbreviation is CLM.

It may be scientifically appropriate to pool data from these samples with data from other ancestrally related groups when the data show that the groups have similar allele frequencies. If the groups are all from the Americas, the recommended designation to describe the combined analysis panel is “Americas” (AMR). If groups are very closely related to the Colombians and have similar allele frequencies, then another abbreviation may be used.

Additional guidance about how to refer to the populations can be found at Guidelines for Referring to the Populations in Publications and Presentations.

Principal Investigators 

  • Gabriel Bedoya - Universidad de Antioquia, Colombia
  • Maria V. Parra - Universidad de Antioquia, Colombia
  • Andrés Ruiz-Linares - University College London

References

  1. Wang S, Ray N, Rojas W, Parra MV, Bedoya G, Gallo C, Poletti G, Mazzotti G, Hill K, Hurtado AM, Camrena B, Nicolini H, Klitz W, Barrantes R, Molina JA, Freimer N, Bortolini MC, Salzano FM, Petzl-Erler ML, Tsuneto LT, Dipierri JE, Alfaro EL, Bailliet G, Bianchi NO, Llop E, Rothhammer F, Excoffier L, Ruiz-Linares A. (2008) Geographic patterns of genome admixture in Latin American Mestizos. PLoS Genet4(3): e1000037.
  2. Bedoya G, Montoya P, Garcia J, Soto I, Bourgeois S, Carvajal L, Labuda D, Alvarez V, Ospina J, Hedrick PW, Ruiz-Linares A. (2006) Admixture dynamics in Hispanics: a shift in the nuclear genetic ancestry of a South American population isolate.Proc Nal. Acad Sci103(19): 7234-7239.
  3. Safford F, Palacios M. (2001) Colombia: Fragmented Land, Divided Society (Latin American Histories). Oxford Univ. Press, Oxford.
  4. Carvajal-Carmona LG, Soto ID, Pineda N, Ortiz-Barrientos D, Duque C, Ospina-Duque J, McCarthy M, Montoya P, Alvarez VM, Bedoya G, Ruiz-Linares A. (2000) Strong Amerind/white sex bias and a possible Sephardic contribution among the founders of a population in northwest Colombia. Am J Hum Genet67(5): 1287-1295.