Finnish in Finland [FIN]

Available Samples Family Relationships
Cell Cultures: 103
   
DNA: 103
   
DNA Sample Panel: MGP00001
   
 
 Unrelated Individuals:  103
   

 
   

 
   
 

Population Description

These cell lines and DNA samples were prepared from blood samples collected from unrelated individuals from Finland. All individuals identified themselves as having at least three out of four grandparents who were born in Finland, and 98% of individuals participating have all four grandparents born in Finland. The participants include some individuals with grandparents born in Finnish Karelia, a part of Finland until 1947, who also represent the Finnish population.

Referring to Populations

The full population descriptor is Finnish in Finland. The shorthand label is Finnish and the abbreviation is FIN.

It may be scientifically appropriate to pool data from these samples with data from other ancestrally related groups, when the data show that the groups have similar allele frequencies. If the groups all have European ancestry, the designation “European ancestry” (EUA) to describe the combined analysis panel is recommended. If only groups very closely related to the Finnish have similar allele frequencies, then another abbreviation may need to be used.

Additional guidance about how to refer to the populations can be found at Guidelines for Referring to the Populations in Publications and Presentations.

Principal Investigator 

  • Leena Peltonen - Wellcome Trust Sanger Institute, Hinxton, UK and University of Helsinki, Helsinki, Finland

References

  1. Jakkula E, Rehnstrom K, Varilo T et al. (2008) The genome-wide patterns of variation expose significant substructure in a founder population. Am J Hum Genet83(6): 787-794.
  2. Kittles RA, Bergen AW, Urbanek M et al. (1999) Autosomal, mitochondrial, and Y chromosome DNA variation in Finland: evidence for a male-specific bottleneck. Am J Phys Anthropol108(4): 381-399.
  3. Norio R (2003a) Finnish Disease Heritage I: characteristics, causes, background. Hum Genet112(5-6): 441-456.
  4. Norio R (2003b) The Finnish Disease Heritage III: the individual diseases. Hum Genet112(5-6): 470-526.
  5. Norio R (2003c) Finnish Disease Heritage II: population prehistory and genetic roots of Finns. Hum Genet112(5-6): 457-469.
  6. Pastinen T, Perola M, Ignatius J et al. (2001) Dissecting a population genome for targeted screening of disease mutations.Hum Mol Genet10(26): 2961-2972.
  7. Peltonen L, Jalanko A, Varilo T (1999) Molecular genetics of the Finnish disease heritage. Hum Mol Genet8(10): 1913-1923.
  8. Service S, Deyoung J, Karayiorgou M et al. (2006) Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies. Nat Genet38(5): 556-560.