Iberian populations in Spain [IBS]

Available Samples Family Relationships
Cell Cultures: 157
DNA: 157
DNA Sample Panel: MGP00010
 Trios:  50
 Unrelated Individuals:  7


Population Description

These cell lines and DNA samples were prepared from blood samples collected throughout the Spanish territory. The total number of geographical areas was 50, corresponding to the 50 administrative provinces (geographical areas surrounding a medium-large city) which constitute Spain, including the area in the Iberian Peninsula as well as the islands. Samples were collected from individuals who identified themselves as having been born in the area and having all four grandparents (two generations) born in the same area.

This set of samples can be viewed as generally representative of the population of Spain, with a broad geographic spread. The overall group contains some individuals from the Basque Country and from the Canary Islands, sometimes regarded as differentiated genetically.

Referring to Populations

The full population descriptor is Iberian Populations in Spain. The shorthand label is Iberian and the abbreviation is IBS.

It may be scientifically appropriate to pool data from these samples with data from other ancestrally related groups, when the data show that the groups have similar allele frequencies. If all the groups have European Ancestry, then the recommended designation to describe the combined analysis panel is “European Ancestry” (abbreviation: EUA). If only groups very closely related to the Iberians have similar allele frequencies, then another abbreviation may be used.

Additional guidance about how to refer to the populations can be found at Guidelines for Referring to the Populations in Publications and Presentations.

Principal Investigator

  • Alberto Orfao -Banco Nacional de ADN, University of Salamanca, Salamanca, Spain


  1. Adams SM, et al. (2008) The genetic legacy of religious diversity and intolerance: paternal lineages of Christians, Jews, and Muslims in the Iberian Peninsula. Am J Hum Genet  83(6): 725-36.
  2. Bauduer F, Feingold J, Lacombe D. (2005) The Basques: review of population genetics and Mendelian disorders. Hum Biol77(5): 619-37.
  3. Bertranpetit J, Cavalli-Sforza LL. (1991) A genetic reconstruction of the history of the population of the Iberian Peninsula.Ann Hum Genet55: 51-67.
  4. Bosch E, et al. (2001) High-resolution analysis of human Y-chromosome variation shows a sharp discontinuity and limited gene flow between northwestern Africa and the Iberian Peninsula. Am J Hum Genet68(4): 1019-29.
  5. Garagnani P, et al. (2009) Isolated populations as treasure troves in genetic epidemiology: the case of the Basques. Eur J Hum Genet17(11): 1490-94.
  6. Plaza S, et al. Joining the pillars of Hercules: mtDNA sequences show multidirectional gene flow in the western Mediterranean. (2003) Ann Hum Genet 67: 312-28.