Mende in Sierra Leone [MSL]

Available Samples Family Relationships
Cell Cultures: 128
   
DNA: 128
   
DNA Sample Panel: MGP00021
   
 
 Trios:  9
   
 Parent-Child Duos:  14
   
 Family of 2 or more:  3
   
 Unrelated Individuals:  61

Population Description

These cell lines and DNA samples were prepared from blood samples collected in Sierra Leone from individuals who identified themselves as Mende. All individuals identified themselves as having four Mende grandparents.

Referring to Populations

It is important to include a reference to “Sierra Leone” when describing the source of these samples. Including the name of the country where these samples were collected reinforces the point that the sample set, while not genetically atypical, does not necessarily represent all Mende people, whose population history is complex. The population should not be described merely as “African”, “Sub-Saharan African”, “West African”, or “Sierra Leonian”, since each of those designators encompasses many populations with different geographic ancestries.

The full population descriptor is Mende in Sierra Leone. The shorthand label is Mende and the abbreviation is MSL.

It may be scientifically appropriate to pool data from these samples with data from other ancestrally related groups, when the data show that the groups have similar allele frequencies. If all of the groups have African Ancestry, the recommended designation to describe the combined analysis panel is "African Ancestry" (abbreviation: AFA). If only groups very closely related to the Mende have similar allele frequencies, then another abbreviation may need to be used.

Additional guidance about how to refer to the populations can be found at Guidelines for Referring to the Populations in Publications and Presentations.

Principal Investigators

  • Robert Garry - Tulane University, New Orleans, LA 
  • Pardis Sabeti - Harvard University, Broad Institute, Cambridge, MA 
  • Donald Grant - Kenema Government Hospital, Kenema, Sierra Leone