Mexican Ancestry in Los Angeles CA USA [MXL]

Available Samples Family Relationships
Cell Cultures: 71
DNA: 71
DNA Sample Panel: MGP00006
 Trios:  30
 Unrelated Individuals:  14


Shared Samples

The 1000 Genomes Project shares some samples with the International HapMap Collection. The Family Relationships listed above includes those samples that were also part of the HapMap Project which can be found here.

Population Description

These cell lines and DNA samples were prepared from blood samples collected in Los Angeles, California from individuals who identified themselves as having at least three out of four grandparents who were born in Mexico. Note that the individuals whose samples are included in this set are different from those who provided samples for the "Mexican-American" panels included in the NIGMS Human Genetic Cell Repository, even though both sets of samples were collected in Los Angeles.

Referring to Populations

It is important to include a reference to "Los Angeles, California" when describing the source of these samples. Including the name of the city and state where these samples were collected reinforces the point that the sample set, while not genetically atypical, does not necessarily represent all people with Mexican ancestry in the United States, nor all Mexican people, whose population history is complex. The population should not be described as "Mexican American" out of respect for the expressed wishes of the donor community. The population also should not be described merely as "Hispanic" or "Latino", since those designations encompass many populations with many different geographic ancestries.

The full population descriptor is Mexican Ancestry in Los Angeles, CA, USA. The shorthand label is Mexican Ancestry and the abbreviation is MXL.

It may be scientifically appropriate to pool data from these samples with data from other ancestrally related groups, when the data show that the groups have similar allele frequencies. If the groups all have Mexican ancestry, the designation "Mexican ancestry" (abbreviation: MXA) to describe the combined analysis panel is recommended. If only groups very closely related to this group of Mexican ancestry individuals have similar allele frequencies, then another abbreviation may need to be used.

Additional guidance about how to refer to the populations can be found at Guidelines for Referring to the Populations in Publications and Presentations. 

Principal Investigator for Community Engagement and Sample Collection   

  • Julio Licinio - University of California at Los Angeles, Los Angeles, CA