How many vials of cell culture from the same specimen or participant can I order?
You may order 1 vial of cell culture from the same specimen or participant per order.
Do you have pairs of CDKL5 iPSCs?
All paired cell lines are listed on the product page. Pricing for ordering pairs of the iPSCs are shown on the page.
Can you describe the WT versus isogenic controls?
During the creation of the patient derived iPSCs from fibroblast, wildtype clones were isolated in addition to mutant clones. As CDKL5 is an X-Linked gene, the female WT clones may not have the wild type gene expressed on the same allele as the mutant due to x-inactivation. These are alternate allele wildtype expressing clones. Eventually, all female mutant lines will have an isogenic control where the mutation is corrected back to wildtype. The wildtype for all male lines shown is the isogenic control as these patients were somatic mosaics.
