Description:
TRANSLOCATED CHROMOSOME
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Repository
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NIGMS Human Genetic Cell Repository
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| Subcollection |
Chromosome Abnormalities |
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Cell Type
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Fibroblast
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Transformant
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Untransformed
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Race
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White
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Family Member
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2
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Relation to Proband
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mother
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Confirmation
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Karyotypic analysis after cell line submission to CCR
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ISCN
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46,XX,t(8;15)(8qter>8p21::15q26>15qter; 15pter>15q26::8p21>8pter)
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Species
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Homo sapiens
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Common Name
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Human
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Remarks
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| Passage Frozen |
3 |
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| IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin Confirmed by Chromosome Analysis |
| |
| Cytogenetics |
Chromosome 15: TRANSLOCATION Breakpoint 15q26 t(8;15)15q26 |
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Chromosome 8: TRANSLOCATION Breakpoint 8p21 t(8;15)8p21 |
| Remarks |
Clinically normal |
| Lin MS, Zhang A, Fujimoto A, Asynchronous DNA replication between 15q11.2q12 homologs: cytogenetic evidence for maternal imprinting and delayed replication. Hum Genet96(5):572-6 1995 |
| PubMed ID: 8530005 |
| |
| Jones LA, Dengler DR, Taysi K, Shackelford GD, Hartmann AF, Partial trisomy of the short arm of chromosome 8 resulting from balanced maternal translocation. J Med Genet17:232-5 1980 |
| PubMed ID: 7401137 |
| Passage Frozen |
3 |
| Split Ratio |
1:5 |
| Temperature |
37 C |
| Percent CO2 |
5% |
| Medium |
Eagle's Minimum Essential Medium with Earle's salts and non-essential amino acids with 2mM L-glutamine or equivalent |
| Serum |
15% fetal bovine serum Not inactivated |
| Substrate |
None specified |
| Subcultivation Method |
trypsin-EDTA |
| Supplement |
- |
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