ND21951

Overview

Repository

NINDS Repository

Subcollection

Motor Neuron Disease
Parkinsonism

Quantity

3 µg

Quantitation Method

Please see our FAQ

Biopsy Source

Peripheral vein

Sample Source

DNA from Whole Blood

Race

White

Subject Type

case-spouse

Family Type

NUCLEAR FAMILIES - ONE AFFECTED

Ethnicity

Not Hispanic/Latino

Country of Origin

POLAND

Family Member

Family History

Relation to Proband

proband

Note

This material represents a finite resource (DNA from Whole Blood)

Phenotypic Data

Demographic Data

Relation to Proband

proband

Age at Sampling

68 YR

Gender

Male

Age of Onset(If not a control)

62 YR

Age at Diagnosis(If not a control)

62 YR

Hispanic or Latino/Not Hispanic or Latino

Not Hispanic/Latino

Racial Category

White

Country

POLAND

Diagnosed By

No Data

Data Elements

Clinical Element Type: Motor Neuron Disorders

(Baseline)

Longitudinal Data

Is this data Longitudinal (Follow-Up) Data?

yes no

Family History

ALS/other MND

present absent unknown

Parkinson's disease

present absent unknown

Alzheimer's disease

present absent unknown

Other dementia

present absent unknown

Other neurodegenerative disease

present absent unknown
Notes: MOTHER HAD GAIT PRBLEMS/PERSONALITY CHANGES

Medical History

Alzheimer's disease

present absent

Ataxia

present absent

Autism

present absent

Bipolar (manic-depressive)

present absent

Brain aneurysm

present absent

Cancer

present absent

Dementia

Alzheimer's
Dementia
absent

Depression

present absent

Diabetes

present absent

Dystonia

present absent

Epilepsy

present absent

Heart disease

present absent

Hypertension

present absent

Multiple sclerosis

present absent

Muscle disease

present absent

Parkinson's

present absent

Schizophrenia

present absent

Suicide/Attempt

present absent

Stroke

present absent

Primary Clinical Diagnosis

Primary clinical diagnosis

Other (specify)
Notes: OVERLAP SYNDROME

Secondary Neurological Diagnosis

Secondary neurological diagnoses

Frontotemporal dementia
Other (specify)
Not Applicable

Notes: ALS, PLS, PARKINSONISM

Site of Symptom Onset

site of symptom onset

Limb-lower

Treatment

Current treatment

Riluzole
PEG
NIPPV
Tracheotomy
Assisted Ventilation > 23 hours
Other (specify)
No Treatment

Signs Supporting Diagnosis

Upper Motor Neuron Signs-Bulbar

definite indeterminate absent not tested

Upper Motor Neuron Signs-Cervical/upper limbs