Description:
TRANSLOCATED CHROMOSOME
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Repository
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NIGMS Human Genetic Cell Repository
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| Subcollection |
Chromosome Abnormalities |
| Quantity |
25 µg |
| Quantitation Method |
Please see our FAQ |
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Biopsy Source
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Peripheral vein
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Cell Type
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B-Lymphocyte
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Tissue Type
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Blood
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Transformant
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Epstein-Barr Virus
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Sample Source
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DNA from LCL
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Race
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White
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Family Member
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1
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Relation to Proband
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mother
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Confirmation
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Karyotypic analysis after cell line submission to CCR
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ISCN
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46,XX,t(10;21)(10qter>10p11.2::21q22.3> 21qter;21pter>21q22.3::10p11.2>10pter)
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Species
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Homo sapiens
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Common Name
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Human
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Remarks
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| IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin Confirmed by Chromosome Analysis |
| |
| Cytogenetics |
Chromosome 10: TRANSLOCATION Breakpoint 10p11 t(10;21)10p11 |
|
Chromosome 21: TRANSLOCATION Breakpoint 21q22 t(10;21)21q22 |
| Remarks |
Clinically normal |
| Ye MH, Saito-Ohara F, Ikeuchi T, High-resolution chromosome R-banding in lymphoblastoid cell lines by the combined use of cell synchronization and ethidium bromide treatment. Jpn J Hum Genet41:203-8 1996 |
| PubMed ID: 8914636 |
| |
| Jenkins EC, Devine-Gage EA, Robakis NK, Yao XL, Brown WT, Houck GE Jr, Wolfe G, Ramakrishna N, Silverman WP, Wisniewski HM, Fine mapping of an Alzheimer disease-associated gene encoding beta-amyloid protein. Biochem Biophys Res Commun151:1-8 1988 |
| PubMed ID: 3279948 |
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