- Contact Us
What is the Allen Cell Collection?
The Allen Cell Collection is a bank of human induced pluripotent stem cells that are currently derived from the WTC parental line released by the Conklin Laboratory at the J. David Gladstone Institute (available through Coriell as GM25256, where you can also find the de-identified patient information associated with the line). Using CRISPR/Cas9, these cells have been endogenously tagged with a fluorescent protein allowing researchers to see individual structures inside of healthy, living human cells with astonishing clarity. The Allen Cell Collection is maintained and administered by the Coriell Institute for Medical Research (Coriell).
Will these lines be available with other fluorescent protein tags/colors?
While the inaugural collection is exclusively green fluorescent protein tagged (EGFP or mEGFP), there are red fluorescent protein tagged lines in the Allen Institute for Cell Science development pipeline (tdTomato (limited number) and mTagRFP-T), which will become available in 2017. For a full list of the structures currently being tagged by the Allen Institute for Cell Science visit their Cell Collection page at http://www.allencell.org/cell-line-catalog.
Is there more data available on these cell lines?
Yes, the Allen Institute for Cell Science is using these lines in their research and they will post a growing body of data on their Allen Cell Explorer website. Extensive quality control data is available and in some cases additional functional studies contributed by collaborators. Visit their Cell Collection page at http://www.allencell.org/cell-line-catalog.
What assistance is available for working with these hiPSC lines?
The Allen Institute for Cell Science’s Culture Protocol is provided as a link on all the cell line catalogue pages and it is also available on the Allen Institute for Cell Science website along with other useful information to help you get these cells flourishing in your own laboratories (http://www.allencell.org/cell-line-catalog).
What do I need to do in order to access a line from the Allen Cell Collection?
Every requestor must execute a simple material transfer agreement and complete the online ordering process.
MTA is Downloadable here:
Commercial entities and academics or non-profits engaged in commercial activities should refer to the section below entitled, “How can I get access to these lines if I work at a commercial company or I am engaged in commercial activities at an academic or non-profit institute?”
What are the fees for access to lines in the Allen Cell Collection?
There is a fee of $600 per fluorescently tagged hiPSC vial for academic or non-profit entities.
How can I get access to these lines if I work at a commercial company or I am engaged in commercial activities at an academic or non-profit institute?
If you work at a for-profit company or an academic or non-profit entity wishing to engage in commercial activities with these cell lines, please contact Customer Service. Commercial activity by an academic or non-profit entity is defined as fee-for-service or sponsored research or other arrangements in which another party has rights to the output of the work performed, even if the work is done by a non-profit. The Allen Institute for Cell Science is open to making their biological materials available to commercial entities for internal research purposes, but please be advised that third-party restrictions on component materials may impact their ability to share certain biological materials.