Title: Progerinin, an optimized progerin-lamin A binding inhibitor, ameliorates premature senescence phenotypes of Hutchinson-Gilford progeria syndrome
Samples Used: AG03198, AG11513, AG11498, AG03199, and AG00038
Title: Establishment human induced pluripotent stem cell line from idiopathic non-familial Parkinson’s disease patient using self-replicating RNA vector
Samples Used: AG20442
Title: Centrosome and ciliary abnormalities in fetal akinesia deformation sequence human fibroblasts
Samples Used: AG05965 and AG01972
Title: SAMMY-seq reveals early alteration of heterochromatin and deregulation of bivalent genes in Hutchinson-Gilford Progeria Syndrome
Samples Used: AG08498 and AG07095
Title: Exploring the potential of chitosan-based particles as delivery-carriers for promising antimicrobial glycolipid biosurfactants
Samples Used: AG22719
Title: Prolonged Glucocorticoid Exposure Does Not Accelerate Telomere Shortening in Cultured Human Fibroblasts
Samples Used: I90-83
Title: LSH mediates gene repression through macroH2A deposition
Samples Used: AG06814
Title: Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer
Samples Used: AG06814
Title: Oxidative cross-linking of fibronectin confers protease resistance and inhibits cellular migration
Samples Used: I90
Title: Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids
Samples Used: AG14048 and I90-10
Title: Lowered Cyclin E levels increase the efficiency and the specificity of capsaicin against
cancerous cells of mesothelium
Samples Used: AG07086
PDF available: here
Title: Generation of human control iPSC line CHOPi004-A from juvenile foreskin fibroblast cells
Samples Used: AG07095
Title: A method for differentiating human induced pluripotent stem cells toward functional cardiomyocytes in 96-well microplates
Samples Used: AG05836
Title: ESCRT-III controls nuclear envelope deformation induced by progerin
Samples Used: AG03512 and AG11513
Title: WRN modulates mRNA translation by influencing mRNA export from the nucleus through its interaction with the export receptor NXF1 in HeLa cancer cell
Samples Used: AG06814
Title: PAI-1-Dependent Inactivation of SMAD4-Modulated Junction and Adhesion Complex in Obese Endometrial Cancer
Samples Used: AG17870
Title: PICALM Rescues Endocytic Defects Caused by the Alzheimer’s Disease Risk Factor APOE4
Samples Used: AG07086
Title: Ascites-induced compression alters the peritoneal microenvironment and promotes metastatic success in ovarian cancer
Samples Used: AG07086
Title: Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13
Samples Used: AG01972 and AG06917
Title: Nucleolar disruption, activation of P53 and premature senescence in POLR3A-mutated Wiedemann-Rautenstrauch syndrome fibroblasts
Samples Used: AG01972
Title: Lamin A‐mediated nuclear lamina integrity is required for proper ciliogenesis
Samples Used: AG01972, AG08466, AG11513, AG06297, AG06917, AG03512, and AG03257
Title: Biological Aging Modulates Cell Migration via Lamin A/C-Dependent Nuclear Motion
Samples Used: AG09558 and AG09602
Title: Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging
Samples Used: AG08434 and AG11725
Title: Novel resveratrol derivatives have diverse effects on the survival, proliferation and senescence of primary human fibroblasts
Samples Used: AG05965
Title: Apolipoprotein D-mediated preservation of lysosomal function promotes cell survival and delays motor impairment in Niemann-Pick type A disease
Samples Used: AG07323
Title: Lysosome Associated Protein Transmembrane 4B (LAPTM4B)-24 is the predominant protein isoform in human tissues and undergoes rapid, nutrient-regulated turnover
Samples Used: AG08498
Title: Cytoskeleton stiffness regulates cellular senescence and innate immune response in Hutchinson–Gilford Progeria Syndrome
Samples Used: AG03513, AG06917,AG08466, AG08468, AG08469, and AG08470
Title: Fully Phased Sequence of a Diploid Human Genome Determined de Novo from the DNA of a Single Individual
Samples Used: AG06814
Title: Generation of human induced pluripotent stem cell line from Alzheimer’s disease patient with PSEN2 N141I mutation using integration-free non-viral method
Samples Used: AG09908
Title: Reacquisition of a spindle cell shape does not lead to the restoration of a youthful state in senescent human skin fibroblasts
Samples Used: AG05397
Title: Reacquisition of a spindle cell shape does not lead to the restoration of a youthful state in senescent human skin fibroblasts
Samples Used: AG16086, AG06240, AG13152, AG13222, AG11572, AG06917, AG07493, and AG10677
Title: Reacquisition of a spindle cell shape does not lead to the restoration of a youthful state in senescent human skin fibroblasts
Samples Used: AG01523
Title: Repetitive elements as a transcriptomic marker of aging: Evidence in multiple datasets and models
Samples Used: AG09843 and AG11748
Title: Pathogenic variants in EP300 and ANKRD11 in patients with phenotypes overlapping Cornelia de Lange syndrome
Samples Used: AG09393 and AG14730
Title: Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties
Samples Used: I90-78
Title: Restoration of lysosomal function after damage is accompanied by recycling of lysosomal membrane proteins
Samples Used: AG01518
Title: BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells
Samples Used: AG16102
Title: Impaired Myofibroblast Dedifferentiation Contributes to Non-Resolving Fibrosis in Aging
Samples Used: I90-83 and I90-53
Title: Bioprospecting Sponge-Associated Marine Cyanobacteria to Produce Bioactive Compounds
Samples Used: AG01523
Title: Hydrogen Peroxide Mediates Artemisinin-Derived C-16 Carba-Dimer-Induced Toxicity of Human Cancer Cells
Samples Used: AG01522
Title: Unraveling LMNA Mutations in Metabolic Syndrome: Cellular Phenotype and Clinical Pitfalls
Samples Used: AG07095 and AG09309
Title: Human-Induced Neurons from Presenilin 1 Mutant Patients Model Aspects of Alzheimer's Disease Pathology
Samples Used: AG09429, AG02262, AG08711, AG08270, and AG08446
Title: Cancer cell-intrinsic function of CD177 in attenuating β-catenin signaling
Samples Used: AG11132
Title: Defective Mitochondrial Pyruvate Flux Affects Cell Bioenergetics in Alzheimer’s Disease-Related Models
Samples Used: AG09908, AG08525, AG08269, and AG09173
Title: Hyaluronidase-2 Regulates RhoA Signalling, Myofibroblast Contractility and other Key Pro-fibrotic Myofibroblast Functions
Samples Used: AG02262
Title: Persistent DNA damage triggers activation of the integrated stress response to promote cell survival under nutrient restriction
Samples Used: AG09319 and AG16409
Title: Activin A-Mediated Regulation of XT-I in Human Skin Fibroblasts
Samples Used: AG14284 and AG13145
Title: PRMT5 silencing selectively affects MTAP-deleted mesothelioma: In vitro evidence of a novel promising approach
Samples Used: AG07086
Title: Genetic correction of Werner syndrome gene reveals impaired pro-angiogenic function and HGF insufficiency in mesenchymal stem cells
Samples Used: AG00780
Title: Dysregulation of the retromer complex system in Down syndrome
Samples Used: AG04823 and AG08498
Title: Venereal Transmission of Vesicular Stomatitis Virus by Culicoides sonorensis Midges
Samples Used: AG08113
Title: Novel and prevalent non-East Asian ALDH2 variants; Implications for global susceptibility to aldehydes’ toxicity
Samples Used: AG07123
Title: A nuclear lamina‐chromatin‐Ran GTPase axis modulates nuclear import and DNA damage signaling
Samples Used: AG01972, AG11498, AG03199 and AG08469
Title: Predicting age from the transcriptome of human dermal fibroblasts
Samples Used: AG08498, AG13153, AG12207, AG13234, AG14251, AG12587, AG13144, AG16102, AG13967, AG16358, AG04386, AG13066, AG04457, AG04063, AG05413, AG16409, AG11745, AG04661, AG11698, AG05274, AG13244, AG06276, AG11484, AG11725, AG11162, AG11730, AG11556, AG11744, AG12954, AG12947, AG11154, AG04143, AG12989, AG09843, AG13962, AG11748, AG12493, AG13349, AG12602, AG04662, AG05247, AG05248, AG10884, AG11732, AG11017, AG11808, AG09975, AG13225, AG04065, AG11735, AG11357, AG06308, AG12597, AG13129, AG07124, AG12588, AG13208, AG09860, AG13065, AG06291, AG04461, AG12788, AG09559, AG07725, AG04054, AG12599, AG04064, AG07478, AG13018, AG09602, AG16086, AG08433, AG09599, AG04059 and AG09605
Title: ATM activation is impaired in human cells defective in RecQL4 helicase activity
Samples Used: AG17524
Title: Frenolicin B Targets Peroxiredoxin 1 and Glutaredoxin 3 to Trigger ROS/4E-BP1-Mediated Antitumor Effects
Samples Used: I91L-16 and AG06173
Title: A disease causing ATLASTIN 3 mutation affects multiple endoplasmic reticulum-related pathways
Samples Used: AG13334 and AG04151
Title: Autophagic cell death restricts chromosomal instability during replicative crisis
Samples Used: AG06814-N
Title: Fibrin-Targeted Polymerized Shell Microbubbles as Potential Theranostic Agents for Surgical Adhesions
Samples Used: AG07086
Title: REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer’s Disease
Samples Used: AG04455, AG08125, AG08379, AG08509, AG14244, AG09173, AG06869, AG07376, AG21158,
Title: Extranuclear DNA accumulates in aged cells and contributes to senescence and inflammation
Samples Used: AG04392, AG04433, AG04525, AG06555, AG02496, AG03058, AG04405, AG10578, AG11513,
Title: Chromosome alignment maintenance requires the MAP RECQL4, mutated in the Rothmund–Thomson
syndrome
Samples Used: AG05013 and AG18371
Title: Corticosteroids inhibit Mycobacterium tuberculosis-induced necrotic host cell death by abrogating
mitochondrial membrane permeability transition
Samples Used: AG05965
Title: Familial Alzheimer’s disease-linked presenilin mutants and intracellular Ca2+ handling: A single-organelle,
FRET-based analysis
Samples Used: AG09908, AG08525, AG06840 and AG08539
Title: Progerin accelerates atherosclerosis by inducing endoplasmic reticulum stress in vascular smooth muscle
cells
Samples Used: AG06297
Title: Analysis of somatic mutations identifies signs of selection during the in vitro aging of primary dermal
fibroblasts
Samples Used: AG13077, AG08433, AG10579 and AG07091
Title: A pleiotropic role for exosomes loaded with the amyloid β precursor protein carboxyl-terminal fragments in
in the brain of Down syndrome patients
Samples Used: AG06922 and AG07095
Title: mTOR hyperactivation in Down Syndrome underlies deficits in autophagy induction, autophagosome
formation, and mitophagy
Samples Used: AG06922, AG07095, AG07096 and AG04823
Title: Sp1 phosphorylation by ATM downregulates BER and promotes cell elimination in response to persistent
DNA damage
Samples Used: AG06173
Title: Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts
Samples Used: AG04110
Title: SCAMP4 enhances the senescent cell secretome
Samples Used: AG04110
Title: Meganuclease targeting of PCSK9 in macaque liver leads to stable reduction in serum cholesterol
Samples Used: AG07095
Title: Disease-associated short tandem repeats co-localize with chromatin domain boundaries
Samples Used: AG06103
Title: Landscape of the complete RNA chemical modifications in the human 80S ribosome
Samples Used: AG04645 and AG03738
Title: Replication stress shapes a protective chromatin environment across fragile genomic regions
Samples Used: I90-15
Title: Merkel cell polyomavirus infection of animal dermal fibroblasts
Samples Used: AG05308, AG05356, and AG06116
Title: LONGO: an R package for interactive gene length dependent analysis for neuronal identity
Samples Used: AG04148
Title: Increased MMP activity in curved geometries disrupts the endothelial cell glycocalyx creating a
proinflammatory environment
Samples Used: AG09799
