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NA14855 DNA from Somatic cell hybrid

Description:

CHROMOSOME 11 REGIONAL MAPPING PANEL SOMATIC CELL HYBRIDS
CHROMOSOME 12 REGIONAL MAPPING PANEL SOMATIC CELL HYBRIDS

Affected:

No Data

Sex:

No Data

Age:

No Data

  • Overview
  • Characterizations
  • Phenotypic Data
  • Publications
  • External Links

Overview

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Repository NIGMS Human Genetic Cell Repository
Subcollection Hybrids
Quantity 0.050mg
Quantitation Method Please see our FAQ
Cell Type Somatic cell hybrid
Transformant Untransformed
Sample Source DNA from Somatic cell hybrid
Confirmation Clinical summary/Case history
ISCN Human/mouse hybrid retaining a human der(11)t(11;12)(q23.3;p13) in 64% of cells and other human chromosomes
Remarks Line PBR-3; produced by fusing human bone marrow, t(11;12)(q23;p13), with HGPRT- RAG mouse cells; 64% of cells retain a human der(11)t(11;12)(q23.3; p13) and other human chromosomes

Characterizations

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IDENTIFICATION OF SPECIES OF ORIGIN Species of Origin Confirmed by Nucleoside Phosphorylase, Glucose-6-Phosphate Dehydrogenase, and Lactate Dehydrogenase Isoenzyme Electrophoresis and by Chromosome Analysis
 

Phenotypic Data

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Remarks Line PBR-3; produced by fusing human bone marrow, t(11;12)(q23;p13), with HGPRT- RAG mouse cells; 64% of cells retain a human der(11)t(11;12)(q23.3; p13) and other human chromosomes

Publications

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Chang ML, Eddy RL, Shows TB, Lau JT, Three genes that encode human beta-galactoside alpha 2,3- sialyltransferases. Structural analysis and chromosomal mapping studies. Glycobiology5:319-25 1995
PubMed ID: 7655169
 
Polakiewicz RD, Munroe DJ, Sait SN, Tycowski KT, Nowak NJ, Shows TB, Housman DE, Page DC, Mapping of ribosomal protein S3 and internally nested snoRNA U15A gene to human chromosome 11q13.3-q13.5. Genomics25:577-80 1995
PubMed ID: 7789996
 
Golden WL, von Kap-Herr C, Kurth B, Wright RM, Flickinger CJ, Eddy R, Shows T, Herr JC, Refinement of the localization of the gene for human intraacrosomal protein SP-10 (ACRV1) to the junction of bands q23-->q24 of chromosome 11 by nonisotopic in situ hybridization. Genomics18:446-9 1993
PubMed ID: 8288254
 
Jani Sait SN, Raimondi SC, Look AT, Gill H, Thirman M, Diaz MO, Shows TB, A t(11;12) 11q23 leukemic breakpoint that disrupts the MLL gene. Genes Chromosomes Cancer7:28-31 1993
PubMed ID: 7688552

External Links

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dbSNP dbSNP ID: 12201
Pricing
International/Commercial/For-profit:
$449.00USD
U.S. Academic/Non-profit/Government:
$263.00USD
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