Included below are two recent publications where researchers have used data from the 1000 Genomes Project to study breast cancer. Breast cancer happens when abnormal cells in the breast begin to grow and multiply uncontrollably and can spread to other parts of the body.
In the first study, researchers used 1000 Genomes Project data to study new ways to predict breast cancer risk with genetic information. They found that their approach was as accurate and cost effective, making breast cancer risk assessment simpler for clinical care.
For more information:
Development and validation of a next-generation sequencing-based method for calculating the breast cancer polygenic risk score PRS313.
The Breast, 2025 | https://doi.org/10.1016/j.breast.2025.104580
In the second study, researchers used the 1000 Genomes Project data to study how breast cancer risk changes with different technologies. The researchers found that even though the overall results are usually similar, technology-specific differences can sometimes change how patients are sorted into different risk groups.
For more information:
Genomic platform specific polygenic risk scores impact breast cancer risk stratification.
Communications Medicine, 2025 | https://doi.org/10.1038/s43856-025-01298-4
