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Chromosome 11
Records Return:  (15)

Catalog IDPercent of Cells
with Chromosome
Cytogenetic DescriptionAdditional Information
GM07298100t(X;11)(Xqter>Xcen::11cen>11qter) (96%) & other human chromosomesLine #2.12; human/HPRT-deficient Chinese hamster lung cell line; selected in medium containing azaserine; retains human chromosomes #4 (28%), #14 (92%), #20 (12%), #21 (64%), & t(X;11)(Xqter>cen> 11qter) in 100% of cells
GM11936100der(16)t(11;16)(q13;p11) (100%)Line CF52-46-6; produced by the fusion of human fibroblast, GM03005, 46,XX,t(11;16) (q13;p11), with HPRT-deficient mouse A9 cells; grown in medium with adenine, aminopterin, and thymidine; retains human der(16)t(11;16) in 100% of cells
GM15827100 Line AND6; produced by the fusion of human lymphoblasts with Chinese hamster ovary line CHOK1; grown in culture medium with 750ug/ml geneticin (G418); this hybrid retains a human chromosome 11 in 100% of cells.
GM1495496der(11)t(11;16)Line CY8; produced by the fusion of human cells, der(11)t(11;16)(q14;q12), with HPRT- and APRT-deficient mouse cell line A9; grown in culture medium containing adenine and azaserine; retains a human der(11)t(11;16)(q14;q12.1) in 96% of the cells and human chromosomes 5, 7, 8, 20, and 21; a human chromosome 3 may be present in very low frequency
GM1048292der(11)t(X;11)(q26;q23) (92%) & 7 (80%)Line MCH110.1 C4; produced by fusing human fibroblast (GM03552) with a 46,X,t(X;11) (Xpter>Xq26::11q23>11qter;11pter>11q23:: Xq26>Xqter) karyo with mouse line A9 cells; selected in HAT medium: 92% cells have human der(11)t(X;11) and 80% have #7
GM1122292der(11)t(11;22)(q24;q12) (92%) & other human chromosomesLine A3EW2-3B; produced by the fusion of IARC-EW2 cells, der(11)t(11;22)(q24; q12), with TK-deficient Chinese hamster a3 cells; grown in HAT medium; retains human der(11)t(11;22) in 92% of cells and other human chromosomes
GM1193892der(11)t(11;18)(p15.4;p11.1) (96%) & other human chromosomesLine PEL16; produced by the fusion of human lymphoblasts, 46,XY,t(11;18) (p15.4;p11.1), with HPRT-deficient mouse myeloma SP2/O-Ag14 cells; grown without selection; retains human der(11)t(11;18) in 92% of cells & other human chromos
GM1194392 Line POR4; produced by the fusion of human fibro, GM04613, 46,XY,t(2;11)(p11; p13) with HPRT-deficient mouse RAG cells; grown in medium without selection; retains human der(11)t(2;11) in 92% of cells & other human chromosomes
GM1193788der(11)t(4;11)(q21;q23) & #4 (77%)Line A3RS; produced by the fusion of lymphoblasts from a patientt with ALL, t(4;11)(q21; q23) and TK-deficient Chinese hamster ovary a3 cells; grown in medium without selection; retains der(11)t(4;11) in 72% of cells and other human chromosomes including #4
GM1250884del(17)(p13.3) (100%) & other human chromosomesLine Br-8; produced by the fusion of human cells from a pt with Miller-Dieker syndrome with TK-def Cl1D mouse cells; grown in HAT medium; retains human del (17)(p13.3) in 100% of cells & other human chromosomes {del(11) & #15}
GM1193976der(16)t(11;16)(p11.2;p11.1) (76%) & other human chromosomesLine 16TX2; product of the fusion of human lymphoblasts, 46,XX,t(11;16)(p11.2; p11.1), GM06316A, with HPRT-deficient mouse myeloma P3/NS-1 cells; grown without selection; retains human der(16)t(11;16) in 76% of cells and other human chromosomes
GM1316076der(16)t(11;16)(p11.2;p11.2) (76%) & 4 (24%)Line CY153; produced by the fusion of human cells, GM06316A, 46,XX,t(11;16) (p11.2;p11.2), with mouse A9 cells; grown in medium with alanosine & adenine; retains human der(16)t(11;16) in 76% of cells & #4 in 24% of cells
GM119446811pter>cent translocated to a hamster chromosome (68%)Line J1-11; produced by the fusion of normal human amniotic fluid cells with Chinese hamster gly-A auxotrophic mutant cells; grown without selection; retains human 11pter>cent translocated to a hamster chromosome in 68% of cells
GM1485564der(11)t(11;12)(q23.3;p13) (64%) & other human chromosomesLine PBR-3; produced by fusing human bone marrow, t(11;12)(q23;p13), with HGPRT- RAG mouse cells; 64% of cells retain a human der(11)t(11;12)(q23.3; p13) and other human chromosomes
GM1497156der(16)Line CY11; produced by the fusion of human fibros, GM03005, 46,XX,t(11;16)(q13;p11), with HPRT- and APRT-deficient mouse A9 cells; culture is grown in medium containing adenine and azaserine; retains a human der(16)t(11;16)(q21;p12.3) in 56% of cells; this hybrid tends to form human/rodent translocations and users who elect to use the culture rather than the DNA sample should monitor the culture for retention of the der(16)

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